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嵌合抗原受体T细胞疗法:从实验室到临床应用

CAR-T Cell Therapy: From the Bench to the Bedside.

作者信息

Golubovskaya Vita

机构信息

Promab Biotechnologies, 2600 Hilltop Drive, Richmond, CA 94806, USA.

出版信息

Cancers (Basel). 2017 Oct 31;9(11):150. doi: 10.3390/cancers9110150.

Abstract

CAR (Chimeric Antigen receptor)-T cell therapy is a novel type of therapy that uses engineered T cells with an antibody single-chain variable fragment (ScFv) extracellular domain that binds tumor-associated antigens[...].

摘要

嵌合抗原受体(CAR)-T细胞疗法是一种新型疗法,它使用经改造的T细胞,这些T细胞带有能结合肿瘤相关抗原的抗体单链可变片段(ScFv)胞外结构域[……]

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