Fridén J, Sfakianos P N, Hargens A R
Department of Hand and Reconstructive Surgery, Umeå University Hospital, Sweden.
J Orthop Res. 1989;7(1):142-5. doi: 10.1002/jor.1100070120.
Serum muscle enzyme activities of eight healthy men (22-32 years old) were measured before and 48 h after separate bouts of repetitive concentric, eccentric, and isometric contractions of the lower leg anterior compartments. Serum creatine kinase and glutamic oxaloacetic acid transaminase levels were both elevated 2 days after the eccentric exercise regimen, exclusively (36 and 17%, respectively). Lactic dehydrogenase levels were not affected by any of the protocols. Delayed muscle soreness was exclusively reported from the eccentrically exercised limb. We suggest that the high tensions developed during eccentric exercise cause mechanical damage, possibly including sarcolemmal degeneration. Subsequently, muscle enzymes are released to the blood. We conclude that postexercise serum levels of some muscle enzymes, at the time of maximal soreness, are qualitative markers of muscle damage.
对8名健康男性（22 - 32岁）小腿前侧肌群进行单独的重复性向心、离心和等长收缩运动，分别在运动前和运动后48小时测量血清肌肉酶活性。离心运动方案后2天，血清肌酸激酶和谷草转氨酶水平均单独升高（分别为36%和17%）。乳酸脱氢酶水平不受任何运动方案的影响。仅离心运动的肢体出现延迟性肌肉酸痛。我们认为，离心运动过程中产生的高张力会导致机械损伤，可能包括肌膜变性。随后，肌肉酶释放到血液中。我们得出结论，在最大酸痛时，运动后血清中某些肌肉酶的水平是肌肉损伤的定性标志物。
