Motoyama T, Watanabe H, Watanabe T, Yamamoto T
Department of Pathology, Niigata University School of Medicine, Japan.
J Urol. 1989 Jan;141(1):187-9. doi: 10.1016/s0022-5347(17)40638-0.
Experimental chemotherapy and radiotherapy were tried in transplanted tumors derived from a paratesticular embryonal rhabdomyosarcoma. There was no significant difference on the therapeutic effect between a combination chemotherapy composed of vincristine, actinomycin D and cyclophosphamide, so-called "VAC" regimen, and a single therapy of radiation. However, morphologic analyses suggest that VAC is effective in embryonal rhabdomyosarcomas in which undifferentiated rhabdomyoblasts predominate, while radiotherapy is preferable for those containing variously differentiated rhabdomyoblasts.
