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The prediction of type 1 diabetes by multiple autoantibody levels and their incorporation into an autoantibody risk score in relatives of type 1 diabetic patients.通过多位自身抗体水平预测 1 型糖尿病,并将其纳入 1 型糖尿病患者亲属的自身抗体风险评分中。
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Diabetologia. 2013 Aug;56(8):1735-42. doi: 10.1007/s00125-013-2934-9. Epub 2013 May 12.
5
Subclinical hypothyroidism and dyslipidemia in children and adolescents with type 1 diabetes mellitus.1 型糖尿病患儿和青少年亚临床甲状腺功能减退症与血脂异常。
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9
Potential celiac disease in type 1 diabetes: a multicenter study.1 型糖尿病患者的潜在乳糜泻:一项多中心研究。
Diabetes Res Clin Pract. 2011 Apr;92(1):53-6. doi: 10.1016/j.diabres.2010.12.028. Epub 2011 Jan 15.
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自身免疫在儿科中的印记:1型糖尿病、乳糜泻、甲状腺炎

The Autoimmunity's Footprint in Pediatrics: Type 1 Diabetes, Coeliac Disease, Thyroiditis.

作者信息

Orzan Anca, Novac Carmen, Mihu Mihaela, Ionescu Tirgoviste Constantin, Balgradean Mihaela

机构信息

"Marie Curie" Emergency Clinical Hospital for Children, Bucharest, Romania.

"Prof. Dr. N. Paulescu" National Institute of Nutrition and Metabolic Diseases, Bucharest, Romania.

出版信息

Maedica (Bucur). 2017 Jun;12(2):136-142.

PMID:29090036
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5649036/
Abstract

The present case report aims to describe and discuss the approach for the management of difficult endotracheal intubation in an adult with Down syndrome undergoing cataract surgery. A 26-year-old female with Down syndrome and a validated diagnosis of cataract requiring surgery was examined in order to assess the degree of difficulty of endotracheal intubation. Patients with Down syndrome have characteristic craniofacial abnormalities which require a thorough pre-operative assessment to anticipate and prepare for a difficult endotracheal intubation. Before the surgery, a series of clinical and paraclinical examinations were conducted. Although cataract surgery generally requires loco-regional anesthesia, in our case it was performed under general anesthesia. Indicators of potentially difficult intubation were macroglossia, prognathism, short neck, limited degree of head extension and obesity. The pre-operative examinations, which revealed a high degree of endotracheal intubation, allowed the anesthetist to achieve a better peri- and intra-operative management of the patient.

摘要

本病例报告旨在描述和讨论一名患有唐氏综合征的成年患者在接受白内障手术时,处理困难气管插管的方法。一名26岁患有唐氏综合征且经确诊需要进行白内障手术的女性接受了检查,以评估气管插管的困难程度。唐氏综合征患者具有典型的颅面畸形,这需要进行全面的术前评估,以预测并为困难气管插管做好准备。手术前,进行了一系列临床和辅助检查。虽然白内障手术通常需要局部区域麻醉,但在我们的病例中是在全身麻醉下进行的。潜在困难插管的指标包括巨舌、下颌前突、短颈、头部伸展受限和肥胖。术前检查显示气管插管难度较高,这使麻醉师能够在围手术期和术中对患者进行更好的管理。