Staples Laura, Milder Tamara, Choi Philip Young-Ill
Haematology Department, The Canberra Hospital, Canberra, ACT, Australia.
Endocrinology Department, The Canberra Hospital, Canberra, ACT, Australia.
Case Rep Hematol. 2017;2017:3476349. doi: 10.1155/2017/3476349. Epub 2017 Sep 27.
We present the case report of a patient with severe polycythaemia associated with tibolone. In our 65-year-old postmenopausal patient who initially presented with haemoglobin 203 g/L [115-160] and haematocrit 0.63 [0.32-0.47], the cessation of tibolone, a synthetic hormone replacement therapy, led to a dramatic and sustained resolution of this patient's polycythaemia to normal haematological values. Tibolone possesses oestrogenic, androgenic, and progestogenic properties. Tibolone therapy may be an infrequently recognized contributor towards polycythaemia in postmenopausal patients presenting to haematology clinics.
我们报告了一例与替勃龙相关的严重红细胞增多症患者的病例。在我们这位65岁的绝经后患者中，其最初血红蛋白为203 g/L[115 - 160]，血细胞比容为0.63[0.32 - 0.47]，停用合成激素替代疗法替勃龙后，该患者的红细胞增多症显著且持续缓解至正常血液学值。替勃龙具有雌激素、雄激素和孕激素特性。在血液科门诊就诊的绝经后患者中，替勃龙治疗可能是导致红细胞增多症的一个较少被认识到的因素。
