Lotufo D, Ritch R, Szmyd L, Burris J E
Department of Ophthalmology, New York Eye and Ear Infirmary, NY 10003.
JAMA. 1989 Jan 13;261(2):249-52.
Of 68 patients who presented between the ages of 10 and 35 years with elevated intraocular pressure, 25 were classified as juvenile ocular hypertension and 43 as juvenile primary open-angle glaucoma. Blacks constituted a greater proportion of the primary open-angle glaucoma patients (47%) than of the ocular hypertensives (20%) and in both groups presented at younger ages than did whites. Myopia was present in 59% of the ocular hypertensives and 73% of the primary open-angle glaucoma patients, of whom 39% had more than 6 diopters of myopia. All eyes of black patients with more than 3 diopters of myopia had glaucomatous defects compared with 52% of such eyes of white patients. Our data suggest that myopia is strongly associated with juvenile open-angle glaucoma and that young black patients with elevated intraocular pressure, especially when myopic, are more susceptible to glaucomatous damage than are whites.
在68例年龄在10至35岁之间且眼压升高的患者中,25例被归类为青少年高眼压症,43例为青少年原发性开角型青光眼。原发性开角型青光眼患者中黑人所占比例(47%)高于高眼压症患者(20%),且两组黑人患者的发病年龄均比白人患者小。高眼压症患者中59%患有近视,原发性开角型青光眼患者中73%患有近视,其中39%的患者近视度数超过6屈光度。近视度数超过3屈光度的黑人患者的所有眼睛均有青光眼性损害,而白人患者此类眼睛的这一比例为52%。我们的数据表明,近视与青少年开角型青光眼密切相关,眼压升高的年轻黑人患者,尤其是近视患者,比白人更容易受到青光眼性损害。