University of Nebraska Medical Center, 921 S. 36th St., Omaha, NE, 68105, USA.
Pritzker School of Medicine at the University of Chicago, 125 S. Green St, #202A, Chicago, IL, 60607, USA.
Arch Womens Ment Health. 2018 Aug;21(4):461-463. doi: 10.1007/s00737-017-0796-8. Epub 2017 Oct 31.
We present a case of domperidone withdrawal in a woman using the medication as a galactagogue. Our primary goal is to increase the literature available to providers who work with women who are breastfeeding. We evaluated a woman presenting to our reproductive psychiatry clinic for consultation regarding anxiety and agitation in the context of domperidone discontinuation. We evaluated the available literature regarding domperidone as a galactagogue, as well as the literature regarding adverse effects. The patient presented with withdrawal symptoms after gradual taper and discontinuation of domperidone. After restarting the medication, her symptoms resolved. She was able to successfully discontinue domperidone with a slow, gradual taper. Domperidone is occasionally used as a galactagogue in women with inadequate milk supply. We report a case in which a woman experienced withdrawal symptoms after domperidone discontinuation.
我们报告了一例因使用催乳药物多潘立酮而停药的病例。我们的主要目的是为那些与哺乳期妇女打交道的医护人员提供更多相关文献。我们评估了一位因焦虑和激动而在我们的生殖精神病学诊所寻求咨询的女性,这些症状与多潘立酮停药有关。我们评估了有关多潘立酮作为催乳药物的现有文献,以及有关不良反应的文献。患者在逐渐减少剂量并停止使用多潘立酮后出现停药症状。重新开始使用该药物后,她的症状得到缓解。她能够成功地通过缓慢、逐渐减少剂量来停止使用多潘立酮。多潘立酮偶尔会被用于乳汁分泌不足的女性催乳。我们报告了一例女性在停止使用多潘立酮后出现停药症状的病例。