Arrivé L, Chang Y C, Hricak H, Brescia R J, Auffermann W, Quivey J M
Department of Radiology, University of California School of Medicine, San Francisco 94143.
Radiology. 1989 Jan;170(1 Pt 1):55-8. doi: 10.1148/radiology.170.1.2909120.
To assess the capability of magnetic resonance (MR) imaging to demonstrate postirradiation changes in the uterus, MR studies of 23 patients who had undergone radiation therapy were retrospectively examined and compared with those of 30 patients who had not undergone radiation therapy. MR findings were correlated with posthysterectomy histologic findings. In premenopausal women, radiation therapy induced (a) a decrease in uterine size demonstrable as early as 3 months after therapy ended; (b) a decrease in signal intensity of the myometrium on T2-predominant MR images, reflecting a significant decrease in T2 relaxation time, demonstrable as early as 1 month after therapy; (c) a decrease in thickness and signal intensity of the endometrium demonstrable on T2-predominant images 6 months after therapy; and (d) loss of uterine zonal anatomy as early as 3 months after therapy. In postmenopausal women, irradiation did not significantly alter the MR imaging appearance of the uterus. These postirradiation MR changes in both the premenopausal and postmenopausal uteri appeared similar to the changes ordinarily seen on MR images of the nonirradiated postmenopausal uterus.
为评估磁共振（MR）成像显示子宫放疗后变化的能力，对23例接受过放射治疗的患者的MR研究进行了回顾性检查，并与30例未接受过放射治疗的患者的研究结果进行了比较。MR检查结果与子宫切除术后的组织学检查结果相关。在绝经前女性中，放射治疗导致：（a）子宫大小减小，早在治疗结束后3个月即可显示；（b）在以T2加权为主的MR图像上，子宫肌层信号强度降低，反映T2弛豫时间显著缩短，早在治疗后1个月即可显示；（c）治疗后6个月，在以T2加权为主的图像上可显示子宫内膜厚度和信号强度降低；（d）早在治疗后3个月，子宫分层结构消失。在绝经后女性中，放疗并未显著改变子宫的MR成像表现。绝经前和绝经后子宫的这些放疗后MR变化，与未接受放疗的绝经后子宫MR图像上通常所见的变化相似。
