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子宫交界区:磁共振成像与子宫切除标本组织学检查的相关性

Junctional zone of the uterus: correlation of MR imaging and histologic examination of hysterectomy specimens.

作者信息

Scoutt L M, Flynn S D, Luthringer D J, McCauley T R, McCarthy S M

机构信息

Department of Diagnostic Imaging, Yale University School of Medicine, New Haven, CT 06510.

出版信息

Radiology. 1991 May;179(2):403-7. doi: 10.1148/radiology.179.2.2014282.

DOI:10.1148/radiology.179.2.2014282
PMID:2014282
Abstract

High-resolution magnetic resonance (MR) images of 12 hysterectomy specimens were correlated with results of light microscopy, image analysis, and immunohistochemical studies to investigate the histologic counterpart of the low-signal-intensity band, or junctional zone (JZ), that surrounds the bright central uterine stripe. All specimens were imaged with a 1.5-T superconducting magnet within 21/2 hours (on average) after hysterectomy. Comparison of histologic findings with measurements obtained at MR imaging indicates that the JZ represents the innermost layer of the myometrium. A threefold increase in percentage of nuclear area was found in the JZ in comparison with the outer myometrium, reflecting an increase in both size and number of nuclei. No difference in distribution of common components of the extracellular space (collagen, laminin, and fibronectin) was found between the two layers.

摘要

对12个子宫切除标本进行高分辨率磁共振(MR)成像,并与光学显微镜检查、图像分析和免疫组织化学研究结果进行关联,以探究围绕明亮的子宫中央条纹的低信号强度带即结合带(JZ)的组织学对应物。所有标本在子宫切除术后平均2.5小时内用1.5-T超导磁体进行成像。组织学检查结果与MR成像测量结果的比较表明,JZ代表子宫肌层的最内层。与外层子宫肌层相比,JZ的核面积百分比增加了两倍,反映出细胞核的大小和数量均有所增加。两层之间细胞外空间的常见成分(胶原蛋白、层粘连蛋白和纤连蛋白)分布没有差异。

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