Micozzi M S, Carter C L, Albanes D, Taylor P R, Licitra L M
Armed Forces Institute of Pathology, Washington, DC 20306-6000.
Am J Public Health. 1989 Jan;79(1):73-5. doi: 10.2105/ajph.79.1.73.
We studied bowel function in relation to 123 breast cancer cases among 7,702 women from the US NHANES I Epidemiologic Follow-up Study. Results suggest a slight increased risk of breast cancer for both decreased frequency of bowel movements (relative risk = 1.5, 95% confidence interval = 0.8, 2.7) and firm stool consistency (RR = 1.8, 95% CI = 1.0, 3.2.) These observations are consistent with an hypothesized association between constipation and increased risk of breast cancer.
我们在美国国家健康与营养检查调查I流行病学随访研究的7702名女性中,对123例乳腺癌病例的肠道功能进行了研究。结果表明,排便频率降低(相对风险=1.5,95%置信区间=0.8,2.7)和大便质地坚硬(RR=1.8,95%CI=1.0,3.2)的女性患乳腺癌的风险略有增加。这些观察结果与便秘和乳腺癌风险增加之间的假设关联相一致。