Lanham G R, Weiss S W, Enzinger F M
Department of Soft Tissue Pathology, Armed Forces Institute of Pathology, Washington, DC 20306-6000.
Am J Surg Pathol. 1989 Jan;13(1):1-10.
We report 75 cases of malignant lymphoma presenting in soft tissue taken from the files of the Armed Forces Institute of Pathology. All histologic subtypes with the exception of lymphoblastic lymphoma were represented. Our findings indicate that virtually any soft tissue site may be involved; there is no sex predilection; and size is not helpful in predicting survival. Among the 55 patients for which race was known, there were no black patients. Thirty-three patients with extensive evaluations at the time of diagnosis had no evidence of disseminated disease, but eight of these exhibited widespread disease within 3 months of diagnosis, and seven of the eight died of disease (median survival, 4 months). The remaining 25 patients had much better outcomes; 18 of 19 with intermediate and high-grade lymphomas were alive and well at a median of 74 months after diagnosis. Some tumors exhibited a propensity for involvement of remote soft tissue sites.
我们从武装部队病理研究所的档案中报告了75例发生于软组织的恶性淋巴瘤病例。除淋巴母细胞淋巴瘤外，所有组织学亚型均有体现。我们的研究结果表明，实际上任何软组织部位都可能受累；不存在性别偏好；肿瘤大小对预测生存无帮助。在已知种族的55例患者中，没有黑人患者。33例在诊断时接受广泛评估的患者没有播散性疾病的证据，但其中8例在诊断后3个月内出现了广泛疾病，8例中有7例死于该疾病（中位生存期4个月）。其余25例患者的预后要好得多；19例中、高级别淋巴瘤患者中有18例在诊断后中位74个月时存活且状况良好。一些肿瘤表现出累及远处软组织部位的倾向。
