The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Nucleic Acids Res. 2018 Jan 4;46(D1):D836-D842. doi: 10.1093/nar/gkx1006.
The Mouse Genome Database (MGD; http://www.informatics.jax.org) is the key community mouse database which supports basic, translational and computational research by providing integrated data on the genetics, genomics, and biology of the laboratory mouse. MGD serves as the source for biological reference data sets related to mouse genes, gene functions, phenotypes and disease models with an increasing emphasis on the association of these data to human biology and disease. We report here on recent enhancements to this resource, including improved access to mouse disease model and human phenotype data and enhanced relationships of mouse models to human disease.
小鼠基因组数据库(MGD;http://www.informatics.jax.org)是一个主要的社区小鼠数据库,通过提供实验室小鼠的遗传学、基因组学和生物学的综合数据,支持基础、转化和计算研究。MGD 是与小鼠基因、基因功能、表型和疾病模型相关的生物参考数据集的来源,这些数据集与人类生物学和疾病的关联越来越受到重视。我们在这里报告了这个资源的最新增强功能,包括改进了对小鼠疾病模型和人类表型数据的访问,并增强了小鼠模型与人类疾病的关系。