Takizawa Shinobu, Sako Makoto, Kishi Kenta, Shigenobu Masashi, Vo-Thanh Giang, Sasai Hiroaki
The Institute of Scientific and Industrial Research (ISIR), Osaka University.
Institut de Chimie Moléculaire et des Matériaux d'Orsay (ICMMO), UMR8182. Laboratoire de Catalyse Moléculaire, Université Paris-Sud, Université Paris Saclay.
Chem Pharm Bull (Tokyo). 2017;65(11):997-999. doi: 10.1248/cpb.c17-00554.
An enantioselective intermolecular Rauhut-Currier (RC) reaction of nitroalkenes with ethyl allenoate has been established with quinidine-derived β-isocupreidine. The present RC reaction afforded α-functionalized allenoates 3 in up to 94% yield with 59% enantiomeric excess (ee).
已利用奎尼丁衍生的β-异铜试剂实现了硝基烯烃与丙烯酸乙酯的对映选择性分子间劳乌特-柯里尔（RC）反应。目前的RC反应以高达94%的产率和59%的对映体过量（ee）得到了α-官能化丙烯酸酯3。
