Tenorio Laura, Palacios Fernando
Departamento de Aparato Digestivo, Hospital Nacional Edgardo Rebagliati Martins. Lima, Perú.
Rev Gastroenterol Peru. 2017 Jul-Sep;37(3):203-208.
To evaluate the efficacy and safety of the endoscopic management of Zenker Diverticulum with IT-Knife 2 device.
prospective and multicenter study (Edgardo Rebagliati Martins National Hospital and Golf Clinic). We included all patients with sintomatic Zenker Diverticulum that were treated with endoscopic cricopharyngeal miotomy from september 2013 until august 2016.
the diverticulum septum was faced with a cap, and then it was cut by the IT-Knife 2 (ENDOCUT Q, effect 3-2-5) until its baseline. Disphagia score was compared before and 1 and 3 months after the procedure.
20 patients were included (11 men; average age: 71 years). The median size of Zenker Diverticulum was 40.5 mm. The median duration of the cricopharyngeal miotomy was 13.75 minutes. Clinical success was 100%. There was a significative decrease (p<0.001) in the disphagia score from 2+/-0.86 before the procedure to 0.05+/-0.22 one month after it. Recurrence after 3 months was 15% and it was completely solved after a second endoscopic treatment. Niether perforation nor bleeding was reported. Two patients had pneumonia.
the endoscopic management of Zenker Diverticulum with IT-Knife 2 is highly effective, safe and less complex than previous technique experience.
评估使用IT-Knife 2设备内镜治疗Zenker憩室的疗效和安全性。
前瞻性多中心研究（埃德加多·雷巴利亚蒂·马丁斯国家医院和高尔夫诊所）。纳入2013年9月至2016年8月间所有接受内镜下环咽肌切开术治疗的有症状Zenker憩室患者。
用帽罩住憩室隔膜，然后用IT-Knife 2（ENDOCUT Q，效果3-2-5）将其切割至基底部。比较术前、术后1个月和3个月的吞咽困难评分。
纳入20例患者（11例男性；平均年龄：71岁）。Zenker憩室的中位大小为40.5毫米。环咽肌切开术的中位持续时间为13.75分钟。临床成功率为100%。吞咽困难评分从术前的2±0.86显著降低（p<0.001）至术后1个月的0.05±0.22。3个月后的复发率为15%，二次内镜治疗后完全解决。未报告穿孔或出血情况。2例患者发生肺炎。
使用IT-Knife 2内镜治疗Zenker憩室高效、安全，且比以往技术经验更简单。
