Pu Qiang-Hong, Lyu Qiu-Ju, Liu Huan, Fan Kai-Hua
Department of Pharmacy Department of Endocrinology, People's Hospital of Leshan, Sichuan, P.R. China.
Medicine (Baltimore). 2017 Nov;96(44):e8247. doi: 10.1097/MD.0000000000008247.
To identify and characterize the top-cited articles in the field of islet transplantation.
We used the Science Citation Index Expanded database to identify the most frequently cited articles published after 1900. Articles were evaluated using the following characteristics: citation number, publication year, study design, references, country and institution of origin, authorship, and journal. Keyword analysis and citation networks were used to analyze research trends.
The most frequently cited articles received between 146 and 2988 citations; the median was 291. All of the most frequently cited articles were published between 1972 and 2012, and 85 articles were published after 1990. The most popular study design involved basic science (75 articles). The leading countries were the United States (US) and Canada, and the leading institutions were the University of Alberta, Canada, and the University of Minnesota, in the US. Journals specializing in diabetes or transplantation published more than half of the articles (n = 53, 52%), with the journal Diabetes publishing the largest number (n = 30). No association was found between a journal's impact factor and the number of top-cited articles it published. There was no correlation between the number of citations and the number of years since publication, authors, participating institutions, or countries involved. Top-cited articles focused on 2 themes: the use of antirejection immunotherapy or biocompatible encapsulations to prolong graft survival, and assessments of the efficacy of islet transplants, in particular, islet allografts.
Our study can help researchers to identify and decipher the characteristics of top-cited articles in the field of islet transplantation. Just as clinically successful allografts are carried out using the Edmonton protocol, autografts and xenografts should be similarly strengthened to solve problems relating to immune rejection and islet sources, respectively.
识别并描述胰岛移植领域被引用次数最多的文章。
我们使用科学引文索引扩展数据库来识别1900年后发表的被引用最频繁的文章。文章根据以下特征进行评估：被引用次数、发表年份、研究设计、参考文献、原产国和机构、作者以及期刊。关键词分析和引文网络用于分析研究趋势。
被引用最频繁的文章被引用次数在146至2988次之间；中位数为291次。所有被引用最频繁的文章均发表于1972年至2012年之间，其中85篇文章发表于1990年之后。最受欢迎的研究设计涉及基础科学（75篇文章）。主要国家是美国和加拿大，主要机构是加拿大阿尔伯塔大学和美国明尼苏达大学。专门研究糖尿病或移植的期刊发表了超过一半的文章（n = 53，52%），其中《糖尿病》期刊发表的文章数量最多（n = 30）。未发现期刊的影响因子与其发表的被引用次数最多的文章数量之间存在关联。被引用次数与发表年份、作者、参与机构或涉及国家的数量之间没有相关性。被引用次数最多的文章集中在两个主题：使用抗排斥免疫疗法或生物相容性封装来延长移植物存活时间，以及评估胰岛移植（特别是胰岛同种异体移植）的疗效。
我们的研究可以帮助研究人员识别和解读胰岛移植领域被引用次数最多的文章的特征。正如使用埃德蒙顿方案进行临床成功的同种异体移植一样，自体移植和异种移植也应分别得到类似加强，以解决免疫排斥和胰岛来源相关问题。
