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与麦角新碱摄入相关的伴有完全性房室传导阻滞的短暂性病态窦房结综合征:一例报告。

Transient sick sinus syndrome with complete atrioventricular block associated with ergonovine intake: A case report.

作者信息

Wang Hui-Ting, Liu Wen-Hao, Chen Yung-Lung

机构信息

Emergency Department Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.

出版信息

Medicine (Baltimore). 2017 Nov;96(44):e8559. doi: 10.1097/MD.0000000000008559.

Abstract

RATIONALE

More mature or older women are more likely to undergo in vitro fertilization and embryo implant. These women have a greater chance of receiving ergonovine therapy because of a suspected abortion. We present this case report to call attention to a latent lethal adverse effect in everyday obstetric practice using ergonovine. It requires more attention and close monitoring PATIENT CONCERNS:: We presented the case of a 38-year-old female patient with general weakness and mild chest tightness after ergonovine use.

DIAGNOSES

She was diagnosed as transient sick sinus syndrome and complete atrioventricular block with junctional escape rhythm after diagnostic work up.

INTERVENTIONS

Conservative treatment with discontinuation of ergonovine and bed rest.

OUTCOMES

Her sinus rhythm returned to normal the day after ergonovine was discontinued. The patient remained symptom-free since recovery of her sinus rhythm.

LESSONS

Ergonovine may cause symptomatic and lethal bradyarrhythmia. Withdrawal of the causative medication and adequate supportive care can lead to a favorable outcome in these patients. More related cases should be reported. Further evaluation for treatment and prognosis are necessary.

摘要

理论依据

年龄较大或更成熟的女性更有可能接受体外受精和胚胎植入。这些女性因疑似流产而接受麦角新碱治疗的可能性更大。我们呈现此病例报告,以引起对日常产科实践中使用麦角新碱时潜在致命不良反应的关注。这需要更多关注和密切监测。患者关注点:我们报告了一名38岁女性患者在使用麦角新碱后出现全身无力和轻度胸闷的病例。

诊断

经过诊断检查,她被诊断为短暂性病态窦房结综合征和完全性房室传导阻滞伴交界性逸搏心律。

干预措施

停用麦角新碱并卧床休息的保守治疗。

结果

停用麦角新碱后第二天,她的窦性心律恢复正常。自窦性心律恢复以来,患者一直无症状。

经验教训

麦角新碱可能导致有症状的致命性缓慢性心律失常。停用致病药物并给予充分的支持治疗可使这些患者获得良好结局。应报告更多相关病例。有必要对治疗和预后进行进一步评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ceb1/5682839/1779a5599339/medi-96-e8559-g001.jpg

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