Sawai Toyomitsu, Yoshioka Sumako, Matsuo Nobuko, Suyama Naofumi, Mukae Hiroshi
Department of Respiratory Medicine, Nagasaki Harbor Medical Center, 6-39 Shinchi-machi, Nagasaki, Japan.
Department of Respiratory Medicine, Nagasaki Harbor Medical Center, 6-39 Shinchi-machi, Nagasaki, Japan.
Int J Surg Case Rep. 2017;41:212-214. doi: 10.1016/j.ijscr.2017.10.027. Epub 2017 Oct 27.
Stenotrophomonas maltophilia usually causes nosocomial infections, but intraabdominal abscesses or organ/space surgical site infection (SSI) secondary to this organism has been rarely reported. Here, we reported a rare case of SSI that presented as intraabdominal abscess caused by S. maltophilia.
A 68-year-old woman presented to our hospital with transverse colon cancer. Further work up with abdominal computed tomography (CT) revealed left renal cell carcinoma. Transverse colon resection and left kidney partial resection were performed. On post-operative day 10, she started to have fever at 38°C and repeat abdominal CT showed intraabdominal abscess. Empiric treatment with piperacillin/tazobactam (TAZ/PIPC) was initiated. However, fever persisted and the abscess size did not change despite 10 days of antibiotic. On post-operative day 20, drainage of intraabdominal abscess was performed. TAZ/PIPC was then shifted to meropenem (MEPM). After two days, S. maltophilia was identified in the culture of the abscess, and MEPM was shifted to minocycline (MINO). Fever disappeared after 7days of treatment and abdominal CT after 14 days showed almost complete resolution of the abscess.
S. maltophilia is a multi-drug resistant, aerobic, non-glucose fermenting, non-sporulating, Gram-negative bacillus. S. maltophilia may cause a variety of infections, but intraabdominal abscesses as a manifestation of SSI due to this organism is relative rare.
Although usually a non-pathogenic organism or colonizer, S. maltophilia can cause organ/space SSI in an immunocompromised host. Therefore, clinicians should be aware of the possibility that S. maltophilia may cause organ/space SSI.
嗜麦芽窄食单胞菌通常引起医院感染,但由该菌引起的腹腔内脓肿或器官/腔隙手术部位感染(SSI)鲜有报道。在此,我们报告一例罕见的由嗜麦芽窄食单胞菌引起的表现为腹腔内脓肿的SSI病例。
一名68岁女性因横结肠癌入住我院。进一步的腹部计算机断层扫描(CT)检查发现左肾细胞癌。遂行横结肠切除术和左肾部分切除术。术后第10天,她开始发热,体温达38°C,复查腹部CT显示腹腔内脓肿。开始使用哌拉西林/他唑巴坦(TAZ/PIPC)进行经验性治疗。然而,尽管使用了10天抗生素,发热仍持续,脓肿大小也未改变。术后第20天,进行了腹腔内脓肿引流。然后将TAZ/PIPC换成美罗培南(MEPM)。两天后,在脓肿培养物中鉴定出嗜麦芽窄食单胞菌,MEPM换成米诺环素(MINO)。治疗7天后发热消失,14天后腹部CT显示脓肿几乎完全消退。
嗜麦芽窄食单胞菌是一种多重耐药、需氧、非葡萄糖发酵、无芽孢、革兰氏阴性杆菌。嗜麦芽窄食单胞菌可能引起多种感染,但由该菌引起的作为SSI表现的腹腔内脓肿相对少见。
尽管嗜麦芽窄食单胞菌通常是一种非致病生物或定植菌,但在免疫功能低下的宿主中可引起器官/腔隙SSI。因此,临床医生应意识到嗜麦芽窄食单胞菌可能引起器官/腔隙SSI的可能性。