Department of Cardiology, First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Metrowest Medical Center, Framingham, 01702, MA, USA.
Adv Exp Med Biol. 2017;1000:9-29. doi: 10.1007/978-981-10-4304-8_2.
Acute coronary syndrome (ACS) is characterized with high morbidity, high mortality, long hospitalization and frequent revisits. It has been the most serious coronary artery diseases in the world. A large body of clinical evidence demonstrates that exercise is associated with reduced cardiovascular disease risk. In addition, different types of exercise have become the central to most cardiac rehabilitation/risk reduction programs. However, the detailed effects of exercise in ACS is still unclear and there is still lack of evidence on which exercise regimen may be ideal for ACS. This chapter presents a brief review of the pathophysiology of ACS and the relationship between exercise and the cardiovascular system. Besides that, this chapter also provide an updated discussion of the most relevant discoveries regarding to exercise and its role in managing ACS in clinical studies.
急性冠状动脉综合征(ACS)的特点是发病率高、死亡率高、住院时间长、复诊频繁。它已成为世界上最严重的冠状动脉疾病。大量临床证据表明,运动与降低心血管疾病风险有关。此外,不同类型的运动已成为大多数心脏康复/降低风险计划的核心。然而,运动对 ACS 的具体影响仍不清楚,也缺乏关于哪种运动方案对 ACS 最理想的证据。本章简要回顾了 ACS 的病理生理学以及运动与心血管系统的关系。此外,本章还就运动在临床研究中对 ACS 的管理作用的最新相关发现进行了讨论。