Amanda Gina, Susanto Agus Dwi, Soehardiman Dicky, Sutoyo Dianiati Kusumo, Lisnawati Yuyun, Busmar Boy, Putra Andika Chandra, Samoedro Erlang, Syahruddin Elisna
Department of Pulmonology and Respiratory Medicine, Faculty of Medicine Universitas Indonesia, Persahabatan Hospital, Jakarta, Indonesia.
Department of Obstetrics and Gynecology, Persahabatan Hospital, Jakarta, Indonesia.
Lung India. 2017 Nov-Dec;34(6):548-551. doi: 10.4103/0970-2113.217574.
Lung cancer during pregnancy is a rare condition. We report a case of 28-year-old nonsmoker female, who was admitted to our hospital with massive left pleural effusion in the 21st week of gestation. Chest radiograph showed total left hemithorax opacity with contralateral mediastinal deviation. Pleural biopsy and cytological examination of pleural fluid revealed adenocarcinoma invasion with positive epidermal growth factor receptor mutation status. Cesarean section was performed at 32 weeks of pregnancy, and targeted therapy was given to this patient after delivery. Computed tomography of the thorax showed a mass lesion in the left hemithorax with liver metastases. Unfortunately, the patient died 10 days after delivery.
妊娠期间患肺癌是一种罕见的情况。我们报告一例28岁不吸烟女性病例，她在妊娠第21周时因大量左侧胸腔积液入住我院。胸部X线片显示左侧全胸透亮度减低，伴有对侧纵隔移位。胸膜活检及胸水细胞学检查显示为腺癌浸润，表皮生长因子受体突变状态为阳性。患者在妊娠32周时行剖宫产，产后接受了靶向治疗。胸部计算机断层扫描显示左胸有一肿块病变并伴有肝转移。不幸的是，患者在产后10天死亡。
