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成人肾病综合征患者孤立性右心室血栓形成:一例报告

Isolated right ventricular thrombus in an adult patient with nephrotic syndrome: a case report.

作者信息

Lempp Severin, Schwenger Vedat

机构信息

Clinic for Kidney, Hypertension and Autoimmune Diseases, Transplant Center Stuttgart, Klinikum Stuttgart, Kriegsbergstraße 60, 70174, Stuttgart, Germany.

出版信息

J Med Case Rep. 2017 Nov 4;11(1):311. doi: 10.1186/s13256-017-1491-0.

DOI:10.1186/s13256-017-1491-0
PMID:29100540
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5670526/
Abstract

BACKGROUND

Venous thrombosis in nephrotic syndrome is a well-described phenomenon. We report a case of an adult patient with an isolated thrombus in the right ventricle due to nephrotic syndrome, which was initially suspected to be a myxoma.

CASE PRESENTATION

A 28-year-old white woman presented to our emergency department with signs of fluid overload. On further evaluation, a right ventricular mass was detected, which was resected and was found to be a thrombus. No other manifestations of venous thrombosis were found. Further evaluation of the patient revealed a nephrotic syndrome, which caused augmented coagulopathy.

CONCLUSIONS

We present a case of a patient in whom a right ventricular mass was the first sign of a renally derived coagulopathy. To the best of our knowledge, this is the first report of an isolated thrombus in the right ventricle due to nephrotic syndrome in an adult. In cases of isolated cardiac thrombi in adults, a further search for renal disease might be helpful to reveal the underlying cause.

摘要

背景

肾病综合征中的静脉血栓形成是一种已被充分描述的现象。我们报告一例成年肾病综合征患者,其右心室出现孤立性血栓,最初被怀疑为黏液瘤。

病例介绍

一名28岁白人女性因液体超负荷症状就诊于我院急诊科。进一步评估发现右心室有一肿块,切除后发现是血栓。未发现静脉血栓形成的其他表现。对该患者的进一步评估显示为肾病综合征,该综合征导致了凝血功能亢进。

结论

我们报告了一例患者,其右心室肿块是肾源性凝血功能障碍的首发症状。据我们所知,这是首例关于成年肾病综合征患者右心室孤立性血栓的报道。对于成人孤立性心脏血栓病例,进一步排查肾脏疾病可能有助于揭示潜在病因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2851/5670526/d09e342147cf/13256_2017_1491_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2851/5670526/d09e342147cf/13256_2017_1491_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2851/5670526/d09e342147cf/13256_2017_1491_Fig1_HTML.jpg

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本文引用的文献

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Intracardiac thrombus--a rare complication of the steroid resistant nephrotic syndrome.心内血栓形成——类固醇抵抗型肾病综合征的一种罕见并发症。
Bratisl Lek Listy. 2008;109(12):573-5.
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The nephrotic syndrome: an unusual case of multiple embolic events.肾病综合征:一例罕见的多发性栓塞事件病例
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Hypercoagulability, renal vein thrombosis, and other thrombotic complications of nephrotic syndrome.高凝状态、肾静脉血栓形成及肾病综合征的其他血栓并发症。
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Right atrial thrombus formation following central venous dialysis catheter placement.中心静脉透析导管置入后右心房血栓形成
Am Surg. 1988 Nov;54(11):652-4.