Corneoplastic Unit, Queen Victoria Hospital, East Grinstead, UK.
Department of Dermatology, Hospital Universitario Infantil Niño Jesus, Madrid, Spain.
Br J Ophthalmol. 2018 May;102(5):586-592. doi: 10.1136/bjophthalmol-2017-310615. Epub 2017 Nov 3.
Congenital ichthyoses (CI) are rare genetic skin keratinisation diseases characterised by generalised scaling and a variable degree of erythema and hyperkeratosis. Ocular involvement includes the eyelids, conjunctiva and all layers of the cornea. Ophthalmic input should include regular slit lamp review with the primary aim to prevent a corneal epithelial defect, secondary bacterial infection, scarring or perforation. This review highlights the current literature regarding ophthalmic findings and management of CI.
先天性鱼鳞病（CI）是一种罕见的遗传性皮肤角化病，其特征为全身性鳞屑和不同程度的红斑和角化过度。眼部受累包括眼睑、结膜和角膜的所有层。眼科评估应包括定期进行裂隙灯检查，主要目的是预防角膜上皮缺损、继发细菌感染、瘢痕或穿孔。本综述重点介绍了关于 CI 的眼科发现和治疗的当前文献。
