Herweh Christian, Nordlohne Stefan, Sykora Marek, Uhlmann Lorenz, Bendszus Martin, Steiner Thorsten
From the Departments of Neuroradiology (C.H., S.N., M.B.), Medical Biometry and Informatics (L.U.), and Neurology (M.S., T.S.), University of Heidelberg, Germany; Department of Neurology, Frankfurt Hoechst Hospital, Frankfurt am Main, Germany (T.S.); and Department of Neurology, St. John's Hospital Vienna, Austria (M.S.).
Stroke. 2017 Dec;48(12):3384-3386. doi: 10.1161/STROKEAHA.117.018779. Epub 2017 Nov 3.
Numerous studies have investigated the influence of meteorologic factors and seasons on the incidence of spontaneous intracerebral hemorrhage (ICH) with ambiguous results. In the present study, data from a large, international multicenter trial in patients with ICH were used to identify seasonal and meteorologic determinants for hypertensive-ICH with greater applicability.
Patients were grouped according to the presumptive ICH cause, that is, hypertensive when located in the basal ganglia brain stem as well as cerebellum and nonhypertensive when located lobar. Both groups were compared with regard to air temperature and air pressure and their occurrence during the year. A regression analysis was performed to identify independent predictors of hypertensive-ICH.
Only hypertensive-ICH showed a seasonal pattern and occurred with higher air pressure values and at younger age. Independent predictors of hypertensive-ICH were increased air pressure on the actual day of the event and younger age as well as higher temperature.
In the present study with an international cohort, besides age air pressure, more than temperature, had an influence on the occurrence of hypertensive-ICH, only.
众多研究探讨了气象因素和季节对自发性脑出血（ICH）发病率的影响，但结果并不明确。在本研究中，来自一项针对ICH患者的大型国际多中心试验的数据被用于确定更具适用性的高血压性ICH的季节和气象决定因素。
患者根据推测的ICH病因进行分组，即位于基底节、脑干以及小脑时为高血压性，位于脑叶时为非高血压性。比较两组的气温、气压及其在一年中的发生情况。进行回归分析以确定高血压性ICH的独立预测因素。
只有高血压性ICH呈现出季节性模式，且在气压较高值时以及较年轻时发生。高血压性ICH的独立预测因素为事件发生当天气压升高、年龄较小以及气温较高。
在本项针对国际队列的研究中，除年龄外，气压而非气温，仅对高血压性ICH的发生有影响。
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