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住院内科患者病床安排至非内科住院病房的死亡率:回顾性队列研究。

Mortality of hospitalised internal medicine patients bedspaced to non-internal medicine inpatient units: retrospective cohort study.

机构信息

Department of Medicine, Queen's University, Kingston, ON, Canada.

Department of Medicine, University of Toronto, Toronto, ON, Canada.

出版信息

BMJ Qual Saf. 2018 Jan;27(1):11-20. doi: 10.1136/bmjqs-2017-006925. Epub 2017 Nov 3.

Abstract

OBJECTIVE

To compare inhospital mortality of general internal medicine (GIM) patients bedspaced to off-service wards with GIM inpatients admitted to assigned GIM wards.

METHOD

A retrospective cohort study of consecutive GIM admissions between 1 January 2015 and 1 January 2016 was conducted at a large tertiary care hospital in Canada.Inhospital mortality was compared between patients admitted to off-service wards (bedspaced) and assigned GIM wards using a Cox proportional hazards model and a competing risk model. Sensitivity analyses included propensity score and pair matching based on GIM service team, workload, demographics, time of admission, reasons for admission and comorbidities.

RESULTS

Among 3243 consecutive GIM admissions, more than a third (1125, 35%) were bedspaced to off-service wards with the rest (2118, 65%) admitted to assigned GIM wards. In hospital, 176 (5%) patients died: 88/1125 (8%) bedspaced patients and 88/2118 (4%) assigned GIM ward patients. Compared with assigned GIM wards patients, bedspaced patients had an HR of 3.42 (95% CI 2.23 to 5.26; P<0.0001) for inhospital mortality at admission, which then decreased by HR of 0.97 (95% CI 0.94 to 0.99; P=0.0133) per day in hospital. Competing risk models and sensitivity analyses using propensity scores and pair matching yielded similar results.

CONCLUSIONS

Bedspaced patients had significantly higher inhospital mortality than patients admitted to assigned GIM wards. The risk was highest at admission and subsequently declined. The results of this single centre study may not be generalisable to other hospitals and may be influenced by residual confounding. Despite these limitations, the relationship between bedspacing and patient outcomes requires investigation at other institutions to determine if this common practice represents a modifiable patient safety indicator.

摘要

目的

比较内科(GIM)患者与分配至 GIM 病房的 GIM 住院患者在服务病房中与不在服务病房中的住院死亡率。

方法

这是一项在加拿大一家大型三级保健医院进行的连续 GIM 入院回顾性队列研究。使用 Cox 比例风险模型和竞争风险模型比较了分配至服务病房(床位)和分配至 GIM 病房的患者之间的住院死亡率。敏感性分析包括基于 GIM 服务团队、工作量、人口统计学、入院时间、入院原因和合并症的倾向评分和配对匹配。

结果

在 3243 例连续 GIM 入院患者中,超过三分之一(1125 例,35%)被分配至服务病房,其余(2118 例,65%)分配至 GIM 病房。住院期间,有 176 名(5%)患者死亡:1125 例床位患者中有 88 例(8%),2118 例分配至 GIM 病房的患者中有 88 例。与分配至 GIM 病房的患者相比,床位患者的住院死亡率的 HR 为 3.42(95%CI 2.23 至 5.26;P<0.0001),随后每天住院的 HR 降低 0.97(95%CI 0.94 至 0.99;P=0.0133)。使用倾向评分和配对匹配的竞争风险模型和敏感性分析得出了类似的结果。

结论

床位患者的住院死亡率明显高于分配至 GIM 病房的患者。入院时风险最高,随后下降。这项单中心研究的结果可能不适用于其他医院,并且可能受到残余混杂因素的影响。尽管存在这些局限性,但床位与患者结局之间的关系需要在其他机构进行调查,以确定这种常见做法是否代表可改变的患者安全指标。

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