Purcell-Jones G, Pither C E, Justins D M
Department of Anaesthetics, St. Thomas' Hospital, London.
Anesth Analg. 1989 Jan;68(1):32-9.
The spread of solution after a standardized paravertebral injection was studied to determine the precision and predictability of paravertebral spread. The spread of 5 ml of a solution of radiological contrast medium (sodium iothalamate) and local anesthetic mixture after 45 (34 thoracic, 11 lumbar) paravertebral injections was studied in 31 patients by radiography and computed tomography and correlated with the clinical effects. Spread confined to the paravertebral area occurred after only eight (18%) injections. Spread was epidural after 31 (70%) injections and exclusively so in 14 (31%) injections. Mean sensory loss was greater after epidural spread, but a wide range of sensation loss was observed with all patterns of spread. Intrapleural spread occurred after three injections, as did spread into the psoas muscle. In addition, measurements were made of 114 paravertebral spaces in 20 patients by means of computed tomography. Dimensional factors identified as possibly leading to complications of a paravertebral injection included narrow width of the thoracic transverse processes (mean, 3.18 cm; range, 2.1-4.2 cm) and the wide range in paravertebral dimensions. The distance from bony landmarks to pleura frequently fell outside the limits recommended by many standard texts. We conclude that the spread of a small volume of solution after paravertebral injection is imprecise and unpredictable. Neurolytic and diagnostic paravertebral injections performed without the aid of radiological imaging and contrast media should be regarded as hazardous and interpreted with extreme caution.
研究标准化椎旁注射后溶液的扩散情况,以确定椎旁扩散的精确性和可预测性。通过放射摄影和计算机断层扫描,在31例患者中研究了45次(34次胸椎、11次腰椎)椎旁注射后5毫升放射造影剂(碘他拉酸钠)和局部麻醉剂混合溶液的扩散情况,并将其与临床效果相关联。仅8次(18%)注射后扩散局限于椎旁区域。31次(70%)注射后扩散至硬膜外,其中14次(31%)完全如此。硬膜外扩散后平均感觉丧失更严重,但所有扩散模式均观察到广泛的感觉丧失范围。3次注射后发生胸膜内扩散,扩散至腰大肌的情况也有3次。此外,通过计算机断层扫描对20例患者的114个椎旁间隙进行了测量。确定可能导致椎旁注射并发症的尺寸因素包括胸椎横突宽度狭窄(平均3.18厘米;范围2.1 - 4.2厘米)以及椎旁尺寸范围广泛。从骨性标志到胸膜的距离常常超出许多标准文献推荐的范围。我们得出结论,椎旁注射后少量溶液的扩散不精确且不可预测。在没有放射成像和造影剂辅助的情况下进行的神经溶解和诊断性椎旁注射应被视为危险操作,并极其谨慎地进行解读。