Rahimi Mahan, Blaber Andrew P, Menon Carlo
MENRVA Research Group, Schools of Mechatronic Systems Engineering and Engineering Science, Simon Fraser University, Metro Vancouver, BC V3T 0A3, Canada.
Aerospace Physiology Laboratory, Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, BC V5A 1S6, Canada.
Med Eng Phys. 2017 Dec;50:65-74. doi: 10.1016/j.medengphy.2017.10.005. Epub 2017 Nov 6.
Notwithstanding the extensive use of conventional compression devices in managing venous disorders, these modalities have shortages that diminish their treatment efficacy and lessen patient adherence to therapy. The purpose of this study was to develop an improved compression system that eliminates the flaws of the existing devices. A motorized bandage was designed that takes advantage of continuous feedback from force-sensing resistors to apply reproducible, controlled pressure on the lower extremities. The performance of the device in enhancing venous return was explored in a pilot test on 11 healthy participants, wherein graded lower body negative pressure was employed as a surrogate of passive standing. Each subject underwent two experiments; with and without pressure application over the calves. A two-way repeated-measures analysis of variance revealed a significant difference in the mean hemodynamic responses when the compression bandage was in action (p < .05). Specifically, a meaningful increase was observed in mean arterial pressure by 5%, diastolic blood pressure by 8% and left ventricular ejection time by 4%; and a significant decrease of 5% and 6% was noticed in heart rate and pulse pressure, respectively. These results demonstrate the capability of the designed system in attenuating the imposed orthostatic stress on cardiovascular system.
尽管传统的加压装置在治疗静脉疾病中被广泛使用,但这些方法存在一些不足,降低了它们的治疗效果并减少了患者对治疗的依从性。本研究的目的是开发一种改进的加压系统,以消除现有装置的缺陷。设计了一种电动绷带,它利用力敏电阻的连续反馈,对下肢施加可重复、可控的压力。在11名健康参与者的初步试验中,研究了该装置在增强静脉回流方面的性能,其中采用分级下身负压作为被动站立的替代方法。每个受试者进行了两个实验,分别是小腿施加压力和不施加压力的情况。双向重复测量方差分析显示,当加压绷带起作用时,平均血流动力学反应存在显著差异(p < 0.05)。具体而言,平均动脉压有意义地升高了5%,舒张压升高了8%,左心室射血时间升高了4%;心率和脉压分别显著降低了5%和6%。这些结果证明了所设计系统减轻心血管系统所承受的直立位应激的能力。