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住院心脏骤停后 Medicare 患者的长期生存趋势:来自 Get With The Guidelines-Resuscitation 的见解。

Long-Term Survival Trends of Medicare Patients After In-Hospital Cardiac Arrest: Insights from Get With The Guidelines-Resuscitation.

机构信息

University of Colorado, Department of Cardiology, Aurora, CO, United States.

Mid-America Heart Institute, Kansas City, MO, United States.

出版信息

Resuscitation. 2018 Feb;123:58-64. doi: 10.1016/j.resuscitation.2017.10.023. Epub 2017 Nov 2.

Abstract

BACKGROUND

Although rates of survival to hospital discharge after in-hospital cardiac arrest (IHCA) have improved over the last decade, it is unknown if these survival gains are sustained after hospital discharge.

OBJECTIVE

To examine 1-year survival trends overall and by rhythm after IHCA.

METHODS

Using Medicare beneficiaries (age≥65years) with IHCA occurring between 2000 and 2011 at Get With The Guidelines®-Resuscitation Registry participating hospitals we used multivariable regression, to examine temporal trends in risk-adjusted rates of 1-year survival.

RESULTS

Among 45,567 patients with IHCA, the unadjusted 1-year survival was 9.4%. Unadjusted 1-year survival was 21.8% among the 9,223 (20.2%) of patients with Ventricular Fibrillation or Pulseless Ventricular Tachycardia (VF/VT) and 6.2% among the 36,344 (79.8%) of patients with Pulseless Electrical Activity or asystole (PEA/asystole). After adjustment for patient and arrest characteristics, 1-year survival increased over time for all IHCA from 8.9% in 2000-2001 to 15.2% in 2011 (adjusted rate ratio [RR] per year, 1.05; 95% CI, 1.03-1.06; P<0.001 for trend). Improvements in 1-year risk adjusted survival were also observed for VF/VT (19.4% in 2000-2001 to 25.6% in 2011 [RR per year, 1.02; 95% CI, 1.01-1.04; P 0.004 for trend]) and PEA/asystole arrests (4.7% in 2000-2001 to 10.2% in 2011 [RR per year, 1.07; 95% CI, 1.05-1.08; P<0.001 for trend]).

CONCLUSION

Among Medicare beneficiaries in the GWTG-Resuscitation registry, 1-year survival after IHCA has increased for over the past decade. Temporal improvements in survival were noted for both shockable and non-shockable presenting arrest rhythms.

摘要

背景

尽管院内心搏骤停(IHCA)后出院存活率在过去十年中有所提高,但尚不清楚这些生存获益是否在出院后得以维持。

目的

检查 IHCA 后整体和按节律的 1 年生存率趋势。

方法

我们使用医疗保险受益人的数据(年龄≥65 岁),这些人在 2000 年至 2011 年间在参与 Get With The Guidelines®-Resuscitation 注册研究的医院发生 IHCA。我们使用多变量回归来检查调整风险后的 1 年生存率的时间趋势。

结果

在 45567 例 IHCA 患者中,未经调整的 1 年生存率为 9.4%。2023 年有 9223 例(20.2%)患者出现心室纤颤或无脉性室性心动过速(VF/VT),未经调整的 1 年生存率为 21.8%,36344 例(79.8%)患者出现无脉性电活动或心搏停止(PEA/asystole),未经调整的 1 年生存率为 6.2%。调整患者和骤停特征后,所有 IHCA 的 1 年生存率随时间推移而增加,从 2000-2001 年的 8.9%增加到 2011 年的 15.2%(调整后每年的发生率比 [RR],1.05;95%置信区间 [CI],1.03-1.06;P<0.001 趋势)。VF/VT 也观察到 1 年风险调整生存率的改善(2000-2001 年的 19.4%至 2011 年的 25.6%[每年 RR,1.02;95%CI,1.01-1.04;P<0.004 趋势])和 PEA/asystole 骤停(2000-2001 年的 4.7%至 2011 年的 10.2%[每年 RR,1.07;95%CI,1.05-1.08;P<0.001 趋势])。

结论

在 GWTG-Resuscitation 注册研究的医疗保险受益人群中,IHCA 后 1 年生存率在过去十年中有所提高。对于可电击和不可电击的呈现节律,均观察到生存时间的改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e66c/5784777/06fa65357cbc/nihms935104f1.jpg

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