比格犬膝关节软骨体积和表面积的测定：一项初步研究。
Determination of knee cartilage volume and surface area in beagle dogs: a pilot study.
作者信息
Dhollander Aad, Malone Amanda, Price James, Getgood Alan
机构信息
The Fowler Kennedy Sport Medicine Clinic, 3M Centre, The University of Western Ontario, London, ON, N6A 3K7, Canada.
AZ Klina, Department of Orthopedic Surgery and Traumatology, Augustijnslei 100, 2930, Brasschaat, Belgium.
出版信息
J Exp Orthop. 2017 Nov 6;4(1):35. doi: 10.1186/s40634-017-0109-1.
BACKGROUND
The objective of this study was to determine the cartilage volume and surface area of male and female Beagle dog knees using 3D (3 dimensional) reconstructed MRI images.
METHODS
Six Beagle Dogs (Canis familiaris) (3 males and 3 females) of 10-18 months old and weighing between 7.2 and 17.1 kg underwent a MRI evaluation of both knees. The data acquired allowed a 3D reconstruction of the knee and measurement of the cartilage volume and surface area.
RESULTS
Mean knee cartilage volume (averaged over the right and left knees) of animals between 7.2 and 17.1 kg ranged from 319.7 to 647.3 mm; while the mean knee cartilage surface area ranged from 427.14 to 757.2 mm. There was evidence of both knee volume and surface area increasing linearly with animal bodyweight.
CONCLUSIONS
The cartilage volume and surface area of the Beagle dog appears to correlate significantly with body weight. This study provides a reference base for future studies investigating cartilage related pathology such as osteoarthritis.
背景
本研究的目的是使用三维（3D）重建的MRI图像确定雄性和雌性比格犬膝关节的软骨体积和表面积。
方法
6只10 - 18月龄、体重在7.2至17.1千克之间的比格犬（犬属）（3只雄性和3只雌性）接受了双膝关节的MRI评估。采集的数据用于膝关节的三维重建以及软骨体积和表面积的测量。
结果
体重在7.2至17.1千克之间的动物，其平均膝关节软骨体积（左右膝关节平均值）在319.7至647.3立方毫米之间；而平均膝关节软骨表面积在427.14至757.2平方毫米之间。有证据表明膝关节体积和表面积均随动物体重呈线性增加。
结论
比格犬的软骨体积和表面积似乎与体重显著相关。本研究为未来研究诸如骨关节炎等软骨相关病理学提供了参考依据。
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