Reshetnikov Aleksei P, Kasatkin Anton A, Urakov Aleksandr L, Baimurzin Dmitrii Y
Departments of Surgery, Dental Clinic ReSto, Izhevsk, Russia.
Department of General and Clinical Pharmacology, Izhevsk State Medical Academy, Izhevsk, Russia.
Dent Res J (Isfahan). 2017 Sep-Oct;14(5):356-358. doi: 10.4103/1735-3327.215967.
Pharmacological sedation is one of the effective ways of prevention of gag reflex development in patients experiencing anxiety and fright before dental treatment. We are reporting a case where we could successfully eliminate exaggerated gag reflex (intravenous [IV] Gagging Severity Index) in a dental patient using IV sedation with dexmedetomidine. IV administration of dexmedetomidine provided elimination of gag reflex at a depth of sedation for the patient with the Richmond Agitation-Sedation Scale score of -2 and -1. The patient received dexmedetomidine 1.0 μg/kg for 10 min and then a continuous infusion of dexmedetomidine 0.4 μg/kg/h. The use of dexmedetomidine for sedation may be an alternative to other pharmacological agents in patients with dental anxiety accompanied by exaggerated gag reflex.
药物镇静是预防牙科治疗前焦虑和恐惧患者出现 gag 反射的有效方法之一。我们报告了一例使用右美托咪定静脉镇静成功消除牙科患者过度 gag 反射(静脉 gag 严重程度指数)的病例。静脉注射右美托咪定在里士满躁动 - 镇静量表评分为 -2 和 -1 的镇静深度下消除了 gag 反射。患者接受 1.0 μg/kg 的右美托咪定静脉注射 10 分钟,然后以 0.4 μg/kg/h 的速度持续输注右美托咪定。对于伴有过度 gag 反射的牙科焦虑患者,使用右美托咪定进行镇静可能是其他药物的替代选择。