Yoshida Harushi, Ayuse Terumi, Ishizaka Satoru, Ishitobi Shingo, Nogami Tomoyuki, Oi Kumiko
Department of Special Care Dentistry, Nagasaki University Hospital of Medicine and Dentistry, Japan.
Tohoku J Exp Med. 2007 Aug;212(4):373-8. doi: 10.1620/tjem.212.373.
The gag reflex is a somatic natural response in which the body attempts to eliminate instruments or agents from the oral cavity by muscle contraction. Some patients suffered from such severe retching that behavioral techniques did not sufficiently reduce gagging in dentistry. In these patients, pharmacological management was thought to be the last alternative to eliminate the reflex. However, the potential of intravenous (IV) sedation as a way to overcome problems in gagging management during prosthodontic (prosthetic) therapy has not been sufficiently explored. We examined the benefit of IV sedation to facilitate prosthodontic treatment for problematic gagging patients intolerable to dental therapy. The subjects were 10 severely retching patients (7 males and 3 females) who received prosthodontic or restorative therapy under propofol IV sedation. The number, location and prognosis of dentures/restorations were reviewed retrospectively. Eight dentures (3 removable and 5 fixed partial dentures) and 22 restorations (18 crowns and 4 inlays) were seated successfully in the oral cavity without serious complications related to IV sedation. The restored teeth were located predominantly in the posterior regions. Throughout the observation period of at least 6 months, no symptoms of postoperative pain or swelling were found. Five of the 10 patients showed improved tolerance to oral inspection, indicating a behavioral adjustment to dental care. In prosthodontic treatment extended to the posterior regions, propofol IV sedation proved useful in managing reflex control.
咽反射是一种躯体自然反应,在此过程中身体试图通过肌肉收缩将口腔内的器械或物质排出。一些患者出现严重的干呕,以至于行为技术在牙科治疗中不足以减轻恶心反应。对于这些患者,药物治疗被认为是消除反射的最后手段。然而,静脉镇静作为克服口腔修复治疗中恶心控制问题的一种方法,其潜力尚未得到充分探索。我们研究了静脉镇静对那些无法耐受牙科治疗且存在恶心问题的患者进行口腔修复治疗的益处。研究对象为10名严重干呕患者(7名男性和3名女性),他们在丙泊酚静脉镇静下接受口腔修复或修复治疗。对假牙/修复体的数量、位置和预后进行了回顾性分析。8副假牙(3副可摘局部假牙和5副固定局部假牙)和22个修复体(18个牙冠和4个嵌体)成功安置在口腔内,未出现与静脉镇静相关的严重并发症。修复的牙齿主要位于后部区域。在至少6个月的观察期内,未发现术后疼痛或肿胀症状。10名患者中有5名对口腔检查的耐受性有所提高,表明对牙科护理的行为调整。在延伸至后部区域的口腔修复治疗中,丙泊酚静脉镇静被证明对反射控制管理有用。