School of Materials Science and Engineering, Beijing Institute of Technology , No. 5 South Street Zhongguancun, Beijing 100081, P. R. China.
Cardiovascular Research Unit, Chris Barnard Division of Cardiothoracic Surgery, 203 Cape Heart Centre, Faculty of Health Sciences, University of Cape Town , Cape Town 7700, South Africa.
Langmuir. 2017 Dec 5;33(48):13821-13827. doi: 10.1021/acs.langmuir.7b03527. Epub 2017 Nov 22.
Both chiral OFm monosubstituted cyclo(l-Glu-l-Glu) and cyclo(d-Glu-d-Glu) display a robust gelation ability in a variety of organic solvents and water. In contrast to an individual enantiomer, their racemate can form rapidly recoverable thixotropic hydrogels with a remarkably shorter thixotropic recovery time. This unexpected thixotropic behavior is induced by the random arrangement of d- and l-enantiomers in the cell units, leading to the formation of "pseudoracemate", noncrystalline self-assemblies in the resulting 3D fibrous network.
手性 OFm 单取代环（l-谷氨酸-l-谷氨酸）和环（d-谷氨酸-d-谷氨酸）在各种有机溶剂和水中均表现出很强的凝胶能力。与单一的对映异构体不同，它们的外消旋体可以快速形成可恢复的触变水凝胶，其触变恢复时间明显更短。这种出乎意料的触变行为是由 d-和 l-对映异构体在单元中的随机排列引起的，导致在所得的 3D 纤维网络中形成“伪外消旋体”、非晶态自组装。
