Ruan Ban-Feng, Ge Wei-Wei, Lin Meng-Xue, Li Qing-Shan
School of Biological and Medical Engineering, Hefei University of Technology, Hefei 230009, China.
Anticancer Agents Med Chem. 2018;18(3):354-366. doi: 10.2174/1871520617666171106130325.
The marine natural products (MNPs) isolated from seaweeds-associated microbial communities have received substantial attention owing to their exceptional nutritional and pharmacology application, such as antiviral, anticancer, antiprotozoal, antifungal, and antibacterial properties and so on. Particularly, there are several MNPs that have been displayed attractive value for the development of novel anticancer agents. This review covers the literature published in the recent 5 years on the novel anticancer MNPs discovered originating from seaweeds, and focused on the chemistry and relative anticancer activities of new MNPs which categorize their source organisms. These seaweed-derived MNPs are categorized based on their origin as brown algae, red algae, cyanobacteria, chlorophyta and others.
从与海藻相关的微生物群落中分离出的海洋天然产物(MNPs)因其特殊的营养和药理学应用,如抗病毒、抗癌、抗原虫、抗真菌和抗菌特性等,受到了广泛关注。特别是,有几种MNPs在新型抗癌药物的开发中显示出了诱人的价值。这篇综述涵盖了近5年发表的关于源自海藻的新型抗癌MNPs的文献,并重点关注了新MNPs的化学性质和相关抗癌活性,这些新MNPs根据其来源生物进行了分类。这些源自海藻的MNPs根据其来源分为褐藻、红藻、蓝藻、绿藻和其他类别。