联合抗真菌治疗在治疗尖端赛多孢中枢神经系统感染中的应用
Combination Antifungal Therapy in the Treatment of Scedosporium apiospermum Central Nervous System Infections.
作者信息
Henao-Martínez Andrés F, Castillo-Mancilla José R, Barron Michelle A, Nichol Aran Cunningham
机构信息
Division of Infectious Diseases, University of Colorado Denver, 12700 E. 19th Avenue, Mail Stop B168, Aurora, CO 80045, USA.
出版信息
Case Rep Infect Dis. 2013;2013:589490. doi: 10.1155/2013/589490. Epub 2013 Apr 29.
Treatment of Scedosporium apiospermum central nervous system (CNS) infection typically consists of an azole in combination with surgical debridement. This approach requires prolonged treatment and carries a high associated mortality. We present two cases of the successful treatment of S. apiospermum CNS infections with the combination of voriconazole and terbinafine.
尖端赛多孢子菌中枢神经系统（CNS）感染的治疗通常包括使用唑类药物联合手术清创。这种方法需要长期治疗且伴有较高的相关死亡率。我们报告两例使用伏立康唑和特比萘芬联合成功治疗尖端赛多孢子菌CNS感染的病例。
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