染色体分离：纺锤体是否全由微管构成？

Chromosome Segregation: Is the Spindle All About Microtubules?

机构信息

Cell Biology and Biophysics Unit, European Molecular Biology Laboratory (EMBL), Meyerhofstrasse 1, 69117 Heidelberg, Germany.

出版信息

Curr Biol. 2017 Nov 6;27(21):R1168-R1170. doi: 10.1016/j.cub.2017.09.022.

DOI:10.1016/j.cub.2017.09.022

PMID:29112871

Abstract

The spindle segregates chromosomes in cell division and it has long been discussed whether it is microtubules alone that build this fundamental molecular machine. Recent work in mouse oocytes now shows that actin filaments co-assemble with microtubules to promote faithful chromosome segregation.

摘要

纺锤体在细胞分裂中分离染色体，长期以来人们一直争论是否只有微管才能构建这种基本的分子机器。最近在小鼠卵母细胞中的研究工作表明，肌动蛋白丝与微管共同组装以促进忠实的染色体分离。