Memon Azhar
Department of Medicine, Unaizah College of Medicine, Qassim University, Unaizah, Saudi Arabia.
Int J Health Sci (Qassim). 2017 Nov-Dec;11(5):26-29.
Determine the frequency of cardiac autonomic neuropathy (CAN) in type 2 diabetics using Bellavere's score system.
The present cross-sectional study was conducted at the Department of Medicine, Isra University Hospital Hyderabad from March to November 2011. Sixty voluntary participants of type 2 diabetes mellitus (DM) were selected through non-probability purposive sampling. Cardiac autonomic nerve function was assessed using Bellavere's score system. The data were analyzed on the Statistix version 10.0 (USA) using Student's t-test, Chi-square test, one-way ANOVA, and Tukey-Cramer test ( ≤ 0.05).
Of 60 diabetics, CAN was observed in 29 (41.4%). Abnormal heart rate variability (HRV), valsalva ratio, 30-15 ratio, blood pressure (BP) response to standing, and handgrip was noted in 43 (61.4%), 27 (38.5%), 17 (24.2%), 5 (7.14%), and 18 (25.7%), respectively. The hemoglobin A1c was negative correlated with HRV, valsalva ratio, 30-15 ratio, and BP response to sustained handgrip; and positively correlated with BP response to standing, systolic BP, and diastolic BP. Duration of DM was not correlated with cardiac autonomic nerve function tests.
The CAN was observed in 29 (41.4%) using Bellavere's score system. The CAN score may be used as feasible and reproducible bedside clinical test in diabetic patients.
使用贝拉韦雷评分系统确定2型糖尿病患者心脏自主神经病变（CAN）的发生率。
本横断面研究于2011年3月至11月在海得拉巴伊斯拉大学医院内科进行。通过非概率目的抽样选取了60名2型糖尿病（DM）自愿参与者。使用贝拉韦雷评分系统评估心脏自主神经功能。数据在Statistix 10.0版本（美国）上进行分析，采用学生t检验、卡方检验、单因素方差分析和图基 - 克莱默检验（P≤0.05）。
60名糖尿病患者中，观察到29例（41.4%）存在CAN。心率变异性（HRV）、瓦尔萨尔瓦比值、30 - 15比值、站立时血压（BP）反应和握力异常的分别有43例（61.4%）、27例（38.5%）、17例（24.2%）、5例（7.14%）和18例（25.7%）。糖化血红蛋白与HRV、瓦尔萨尔瓦比值、30 - 15比值以及持续握力时的血压反应呈负相关；与站立时血压反应、收缩压和舒张压呈正相关。糖尿病病程与心脏自主神经功能测试无关。
使用贝拉韦雷评分系统观察到29例（41.4%）存在CAN。CAN评分可作为糖尿病患者可行且可重复的床边临床检测方法。
