Gutiérrez Sánchez Daniel, Leiva-Santos Juan P, Cuesta-Vargas Antonio I
1 Cudeca Foundation, Málaga, Spain.
2 Hospital of Manacor, Manacor, Spain.
Clin Nurs Res. 2019 Jun;28(5):583-601. doi: 10.1177/1054773817740671. Epub 2017 Nov 8.
Patients with chronic kidney disease (CKD) Stage 5, experience multiple symptoms that negatively affect the health-related quality of life (HRQoL). This study examined the cluster of symptoms and their association with disease severity and comorbidities. The study sample included 123 patients with CKD Stage 5; 60 patients were in the dialysis group and 63 patients in the Conservative Kidney Management group. Symptom data were collected using the Spanish modified version of Palliative Care Outcome Scale-Symptoms (POS-S) Renal, a validated questionnaire to assess symptoms in this population. More than half of the patients described weakness, difficulty sleeping, and feeling depressed. Two symptom clusters were identified. There was no significant statistical correlation between disease severity and symptoms and between comorbidities and symptoms. The tendency of these symptoms to occur together has implications for improving symptom management in this population. Routine symptom assessment can be useful in clinical and research settings.
慢性肾脏病（CKD）5期患者会出现多种对健康相关生活质量（HRQoL）产生负面影响的症状。本研究调查了症状群及其与疾病严重程度和合并症的关联。研究样本包括123例CKD 5期患者；60例患者在透析组，63例患者在保守肾脏管理组。使用西班牙语版改良姑息治疗结果量表-症状（POS-S）肾脏版收集症状数据，这是一份经过验证的用于评估该人群症状的问卷。超过一半的患者表示有虚弱、睡眠困难和情绪低落的症状。识别出两个症状群。疾病严重程度与症状之间以及合并症与症状之间均无显著统计学相关性。这些症状同时出现的趋势对改善该人群的症状管理具有重要意义。常规症状评估在临床和研究环境中可能会有所帮助。
