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急性胆源性胰腺炎后早期行腹腔镜胆囊切除术可加速康复。

Early laparoscopic cholecystectomy following acute biliary pancreatitis expedites recovery.

作者信息

Eğin Seracettin, Yeşiltaş Metin, Gökçek Berk, Tezer Hakan, Karahan Servet Rüştü

机构信息

Department of General Surgery, Okmeydanı Training and Research Hospital, İstanbul-Turkey.

出版信息

Ulus Travma Acil Cerrahi Derg. 2017 Nov;23(6):495-500. doi: 10.5505/tjtes.2017.50128.

Abstract

BACKGROUND

In this retrospective study, we aimed to assess the reliability of early cholecystectomy, risk of recurrent biliary pancreatitis, and their effects on hospital length of stay and morbidity by comparing the results of early and late laparoscopic cholecystectomy in patients with acute biliary pancreatitis.

METHODS

A total of 131 patients, who were diagnosed with acute biliary pancreatitis at Okmeydanı Education and Research Hospital in January 2009-December 2012, were included in the study. Demographic specifications of patients, duration of their complaints, biochemistry and hemogram values at first arrival, Ranson criteria, number of attacks, screenings, operation type and period, number of days between the first attack and operation, hospital length of stay, and complications were recorded. Patients who underwent cholecystectomy within the first 2 weeks were considered early (group 1) and those who under the operation after 2 weeks were considered late (group 2).

RESULTS

There were 47 patients in group 1 and 84 patients in group 2. Open surgery was not performed on any patient, and there was no choledoch injury and mortality. The average hospital length of stay was 7.6±3.0 days in group 1 and 10.7±8.3 days in group 2, with a statistically significant difference between the groups (p=0.006). Two or more number of attacks occurred in 15 patients in group 2 (18%), with a statistically significant difference between the groups (p=0.000).

CONCLUSION

Laparoscopic cholecystectomy is safe as it does not increase operation time and morbidity in biliary pancreatitis with a Ranson score of ≤3 or cause difficulty in dissection. Late cholecystectomy causes recurrent attacks and increases the hospital length of stay and treatment costs. Using randomized controlled studies, the effectiveness and reliability of early cholecystectomy in mild and moderate biliary pancreatitis can be verified.

摘要

背景

在这项回顾性研究中,我们旨在通过比较急性胆源性胰腺炎患者早期和晚期腹腔镜胆囊切除术的结果,评估早期胆囊切除术的可靠性、复发性胆源性胰腺炎的风险及其对住院时间和发病率的影响。

方法

共有131例于2009年1月至2012年12月在奥克梅伊达尼教育与研究医院被诊断为急性胆源性胰腺炎的患者纳入本研究。记录患者的人口统计学特征、主诉持续时间、首次就诊时的生化和血常规值、兰森标准、发作次数、检查、手术类型和时间、首次发作与手术之间的天数、住院时间以及并发症。在最初2周内接受胆囊切除术的患者被视为早期(第1组),在2周后接受手术的患者被视为晚期(第2组)。

结果

第1组有47例患者,第2组有84例患者。所有患者均未进行开放手术,且无胆总管损伤和死亡病例。第1组的平均住院时间为7.6±3.0天,第2组为10.7±8.3天,两组之间差异有统计学意义(p=0.006)。第2组有15例患者(18%)发生两次或更多次发作,两组之间差异有统计学意义(p=0.000)。

结论

腹腔镜胆囊切除术是安全的,因为它不会增加兰森评分≤3的胆源性胰腺炎的手术时间和发病率,也不会导致解剖困难。晚期胆囊切除术会导致复发,并增加住院时间和治疗费用。通过随机对照研究,可以验证早期胆囊切除术在轻度和中度胆源性胰腺炎中的有效性和可靠性。

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