Heat Transfer and Thermal Power Laboratory, Department of Mechanical Engineering, Indian Institute of Technology Madras, Chennai, 600036, Tamil Nadu, India.
Int J Numer Method Biomed Eng. 2018 Apr;34(4):e2937. doi: 10.1002/cnm.2937. Epub 2017 Nov 27.
Infants born with univentricular heart disease undergo Fontan surgery to establish separate systemic and pulmonary circulations. This surgery results in better blood circulation across a single ventricle that supplies oxygenated blood to the body and passively returns venous blood to the lungs through the total cavopulmonary connection (TCPC). Reducing the pressure drop across the TCPC during Fontan circulation helps in reducing the work load of univentricular heart, and various designs have been proposed for this purpose. The goal of this work is to analyze the effect of placing a porous insert at an appropriate position in the pulmonary artery, on the pressure drop across the TCPC. A 3D computational model of a total TCPC connection provided with a porous insert is developed and solved by finite volume method, under assumptions of steady, laminar, and Newtonian flows. The effects of the porous medium properties-porosity and permeability-across the connection, are analyzed. Compared to the no-porous medium case, TCPC with the porous medium insert exhibits a maximum reduction of 27% in energy loss for the flow range studied. The porous medium used in TCPC connection lowers the energy dissipation by curtailing the flow recirculation zones across the connection. The influences of the diameter of the blood vessel, total cardiac output, and the thickness, permeability, and position of porous media on energy loss are analyzed. The criteria to select the porous medium properties and position for a given Fontan geometry are also determined.
患有单心室心脏病的婴儿接受 Fontan 手术,以建立独立的体循环和肺循环。该手术可改善单个心室的血液循环,为全身提供含氧血液,并通过全腔静脉肺动脉连接(TCPC)被动地将静脉血回流到肺部。降低 Fontan 循环过程中 TCPC 的压降有助于降低单心室的工作负荷,为此提出了各种设计。这项工作的目的是分析在肺动脉的适当位置放置多孔插入物对 TCPC 压降的影响。通过有限体积法开发并求解了带有多孔插入物的总 TCPC 连接的 3D 计算模型,假设为稳态、层流和牛顿流。分析了连接中多孔介质特性-孔隙率和渗透性的影响。与无多孔介质情况相比,在研究的流动范围内,带有多孔介质插入物的 TCPC 的能量损失最大减少了 27%。TCPC 中的多孔介质通过限制连接两侧的回流区来降低能量耗散。分析了血管直径、总心输出量以及多孔介质的厚度、渗透性和位置对能量损失的影响。还确定了为给定的 Fontan 几何形状选择多孔介质特性和位置的标准。