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精神分裂症和双相情感障碍的遗传风险与婴儿神经运动发育的关联。

Association of Genetic Risk for Schizophrenia and Bipolar Disorder With Infant Neuromotor Development.

作者信息

Serdarevic Fadila, Jansen Philip R, Ghassabian Akhgar, White Tonya, Jaddoe Vincent W V, Posthuma Danielle, Tiemeier Henning

机构信息

Department of Child and Adolescent Psychiatry, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, the Netherlands.

Department of Complex Trait Genetics, Center for Neuroscience and Cognitive Research, Amsterdam Neuroscience, VU University, Amsterdam, the Netherlands.

出版信息

JAMA Psychiatry. 2018 Jan 1;75(1):96-98. doi: 10.1001/jamapsychiatry.2017.3459.

DOI:10.1001/jamapsychiatry.2017.3459
PMID:29117282
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5833534/
Abstract

This study uses data from the population-based Generation R Study of Rotterdam, the Netherlands, to assess an association of genetic risk for schizophrenia and bipolar disorder with infant neuromotor development.

摘要

本研究使用了来自荷兰鹿特丹基于人群的Generation R研究的数据，以评估精神分裂症和双相情感障碍的遗传风险与婴儿神经运动发育之间的关联。

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本文引用的文献

1
Polygenic scores for schizophrenia and educational attainment are associated with behavioural problems in early childhood in the general population.精神分裂症和受教育程度的多基因评分与普通人群幼儿期的行为问题有关。
J Child Psychol Psychiatry. 2018 Jan;59(1):39-47. doi: 10.1111/jcpp.12759. Epub 2017 Jun 19.
2
Impairments of motor function among children with a familial risk of schizophrenia or bipolar disorder at 7 years old in Denmark: an observational cohort study.丹麦7岁时具有精神分裂症或双相情感障碍家族风险的儿童的运动功能损害：一项观察性队列研究。
Lancet Psychiatry. 2017 May;4(5):400-408. doi: 10.1016/S2215-0366(17)30103-7. Epub 2017 Mar 23.
3
The Generation R Study: design and cohort update 2017.代际R研究：2017年设计与队列更新
Eur J Epidemiol. 2016 Dec;31(12):1243-1264. doi: 10.1007/s10654-016-0224-9. Epub 2017 Jan 9.
4
Research Review: Do motor deficits during development represent an endophenotype for schizophrenia? A meta-analysis.研究综述：发育过程中的运动缺陷是否代表精神分裂症的一种内表型？一项荟萃分析。
J Child Psychol Psychiatry. 2016 Apr;57(4):446-56. doi: 10.1111/jcpp.12479. Epub 2015 Nov 18.
5
Maternal symptoms of anxiety during pregnancy affect infant neuromotor development: the generation R study.孕期母亲的焦虑症状会影响婴儿神经运动发育：Generation R研究
Dev Neuropsychol. 2009;34(4):476-93. doi: 10.1080/87565640902964508.
6
A developmental model for similarities and dissimilarities between schizophrenia and bipolar disorder.精神分裂症与双相情感障碍异同的一种发育模型。
Schizophr Res. 2004 Dec 1;71(2-3):405-16. doi: 10.1016/j.schres.2004.03.002.