School of Life Sciences, Arizona State University, Tempe, AZ 85287, USA.
School of Molecular Sciences, Arizona State University, Tempe, AZ 85287, USA.
Biol Lett. 2017 Nov;13(11). doi: 10.1098/rsbl.2017.0309.
We used quantitative genetics to test a controversial theory of heat stress, in which animals overheat when the demand for oxygen exceeds the supply. This theory, referred to as oxygen- and capacity-limited thermal tolerance, predicts a positive genetic correlation between hypoxia tolerance and heat tolerance. We demonstrate the first genetic correlation of this kind in a model organism, Genotypes more likely to fly under hypoxic stress (12% O) were also more likely to fly under heat stress (39°C). This finding prompts new questions about mechanisms and limits of adaptation to heat stress.
我们运用数量遗传学验证了一个颇具争议的热应激理论，该理论认为动物在耗氧量超过供应量时会过热。这个理论被称为氧气和能力限制的热耐受，预测了低氧耐受性和耐热性之间存在正的遗传相关性。我们在一个模式生物中首次证明了这种遗传相关性，在低氧应激（12% O）下更有可能飞行的基因型在热应激（39°C）下也更有可能飞行。这一发现引发了关于适应热应激的机制和限制的新问题。
