Ihle-Hansen Håkon, Vigen Thea, Berge Trygve, Einvik Gunnar, Aarsland Dag, Rønning Ole Morten, Thommessen Bente, Røsjø Helge, Tveit Arnljot, Ihle-Hansen Hege
Department of Medical Research, Bærum Hospital, Vestre Viken Hospital Trust, Drammen, Norway.
Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Dement Geriatr Cogn Dis Extra. 2017 Sep 28;7(3):318-327. doi: 10.1159/000480496. eCollection 2017 Sep-Dec.
To investigate Montreal Cognitive Assessment (MoCA) test scores in a cohort aged 63-65 years from a general population in relation to the proposed cut-off score of 26 for mild cognitive impairment (MCI) and to explore the impact of education.
MoCA scores were assessed in the Akershus Cardiac Examination 1950 Study, a cross-sectional cohort study of all men and women born in 1950 living in Akershus County, Norway. The participants were aged 63-65 at the time of data collection.
MoCA scores were available in 3,413 participants, of which 47% had higher education (>12 years). The mean MoCA score was 25.3 (95% confidence interval [CI] 25.2-25.4), and 49% had a score below the suggested cut-off of 26 points. Those with higher education had significantly higher scores (mean 26.2, 95% CI 26.1-26.3 vs. 24.4, 95% CI 24.3-24.6, p < 0.001).
Approximately 50% scored below the cut-off score of 26 points, suggesting that the cut-off score may have been set too high to distinguish normal cognitive function from MCI. Educational level had a significant impact on MoCA scores.
在一个来自普通人群、年龄在63 - 65岁的队列中，研究蒙特利尔认知评估（MoCA）测试分数与提议的轻度认知障碍（MCI）临界值26分之间的关系，并探讨教育程度的影响。
在1950年阿克什胡斯心脏检查研究中评估MoCA分数，这是一项对居住在挪威阿克什胡斯郡、出生于1950年的所有男性和女性进行的横断面队列研究。在数据收集时，参与者年龄为63 - 65岁。
3413名参与者有MoCA分数，其中47%接受过高等教育（>12年）。MoCA分数的平均值为25.3（95%置信区间[CI] 25.2 - 25.4），49%的参与者分数低于建议的临界值26分。受过高等教育的参与者分数显著更高（平均值26.2，95% CI 26.1 - 26.3，对比24.4，95% CI 24.3 - 24.6，p < 0.001）。
约50%的参与者分数低于26分的临界值，这表明该临界值可能设定过高，无法区分正常认知功能与MCI。教育程度对MoCA分数有显著影响。
