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脐动脉肌酸激酶脑型同工酶作为新生儿脑室周围-脑室内出血的预测指标。

Umbilical artery creatine kinase brain-band isozyme as a predictor of neonatal periventricular-intraventricular hemorrhage.

作者信息

Bardeguez A, Tejani N, Verma U L, Kim S J

机构信息

Department of Obstetrics and Gynecology, Nassau County Medical Center, East Meadow, NY.

出版信息

Am J Obstet Gynecol. 1989 Jan;160(1):202-6. doi: 10.1016/0002-9378(89)90121-x.

DOI:10.1016/0002-9378(89)90121-x
PMID:2912083
Abstract

In low-birth-weight neonates, an elevation in the percentage of creatine kinase brain-band isozyme in the umbilical artery was significantly correlated with future development of neonatal grade III and grade IV periventricular-intraventricular hemorrhage, when compared with levels in those neonates who did not show periventricular-intraventricular hemorrhage or who developed grade I and grade II periventricular-intraventricular hemorrhage (p = 0.025). In these neonates the relative levels in maternal venous, umbilical arterial, and umbilical venous samples indicated that the source of the isozyme was fetal.

摘要

在低体重新生儿中,与未发生脑室周围-脑室内出血或发生Ⅰ级和Ⅱ级脑室周围-脑室内出血的新生儿相比,脐动脉中肌酸激酶脑型同工酶百分比升高与Ⅲ级和Ⅳ级脑室周围-脑室内出血的未来发生显著相关(p = 0.025)。在这些新生儿中,母体静脉、脐动脉和脐静脉样本中的相对水平表明同工酶来源是胎儿。

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