Stephens John D, Adam Murtaza K, Todorich Bohzo, Faia Lisa J, Garg Sunir, Dunn James P, Mehta Sonia
Ophthalmic Surg Lasers Imaging Retina. 2017 Nov 1;48(11):894-901. doi: 10.3928/23258160-20171030-04.
To describe spectral-domain optical coherence tomography (SD-OCT) findings in eyes with endogenous fungal chorioretinitis and endophthalmitis.
Retrospective, observational case series of subjects at Wills Eye Hospital and William Beaumont Hospital were identified by screening OCT billing data and cross-referencing with patient charts. Clinical and imaging data were collected for each patient and reviewed.
Twelve eyes of seven consecutive patients were identified, demonstrating two patterns of posterior ocular involvement: chorioretinal infiltration and superficial retinal/retinal vascular infiltration without choroidal involvement. Six of 12 eyes had follow-up imaging performed after antifungal treatment, which demonstrated decreased size of choroidal and/or retinal infiltrates.
All patients with follow-up imaging had anatomic improvement by OCT of the lesions with treatment. In the future, OCT imaging may provide a method to assess therapeutic response and prognosis for visual recovery in patients with endogenous fungal ocular disease. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:894-901.].
描述内源性真菌性脉络膜视网膜炎和眼内炎患者的频域光学相干断层扫描（SD-OCT）表现。
通过筛查OCT计费数据并与患者病历交叉对照，确定了威尔斯眼科医院和威廉·比莫恩特医院的回顾性观察病例系列。收集并回顾了每位患者的临床和影像数据。
共确定了7例连续患者的12只眼，表现出两种后部眼部受累模式：脉络膜视网膜浸润和无脉络膜受累的浅表视网膜/视网膜血管浸润。12只眼中有6只在抗真菌治疗后进行了随访成像，显示脉络膜和/或视网膜浸润灶大小减小。
所有接受随访成像的患者经治疗后，病变在OCT上均有解剖学改善。未来，OCT成像可能为评估内源性真菌性眼病患者的治疗反应和视觉恢复预后提供一种方法。[《眼科手术、激光与视网膜成像》。2017年；48:894 - 901。]
