Song Qiao Feng, Liu Xiao Xue, Hu Wan Ning, Han Xiao Chen, Zhou Wen Hua, Lu Ai Dong, Wang Xi Zhu, Wu Shou Ling
Department of Cardiology, Tangshan People's Hospital, North China University of Science and Technology, Tangshan 063000, Hebei, China.
The Cancer Institute, Tangshan People's Hospital, Tangshan 063000, Hebei, China; Department of Head and Neck Surgery, Tangshan People's Hospital, Tangshan 063000, Hebei, China.
Biomed Environ Sci. 2017 Oct;30(10):749-757. doi: 10.3967/bes2017.100.
Although sleep is one of the most important health-related behavioral factors, the association between night sleep duration and cognitive impairment has not been fully understood. A cross-sectional study was conducted with a random sample of 2,514 participants (⋝ 40 years of age; 46.6% women) in China to examine the association between night sleep duration and cognitive impairment.
Night sleep duration was categorized as ⋜ 5, 6, 7, 8, or ⋝ 9 h per night. Cognitive function was measured using the Mini-Mental State Examination. A multivariate regression analysis was used to analyze the association of night sleep duration with cognitive impairment. A total of 122 participants were diagnosed with cognitive impairment.
A U-shaped association between night sleep duration and cognitive impairment was found. The odds ratios (95% confidence intervals) of cognitive impairment (with 7 h of daily sleep being considered as the reference) for individuals reporting ⋜ 5, 6, 8, and ⋝ 9 h were 2.14 (1.20-3.83), 1.13 (0.67-1.89), 1.51 (0.82-2.79), and 5.37 (1.62-17.80), respectively (P ⋜ 0.01).
Short or long night sleep duration was an important sleep-related factor independently associated with cognitive impairment and may be a useful marker for increased risk of cognitive impairment..
尽管睡眠是与健康相关的最重要行为因素之一，但夜间睡眠时间与认知障碍之间的关联尚未完全明确。在中国对2514名参与者（年龄≥40岁；女性占46.6%）进行了一项横断面研究，以探讨夜间睡眠时间与认知障碍之间的关联。
夜间睡眠时间分为每晚≤5、6、7、8或≥9小时。使用简易精神状态检查表测量认知功能。采用多因素回归分析来分析夜间睡眠时间与认知障碍之间的关联。共有122名参与者被诊断为认知障碍。
发现夜间睡眠时间与认知障碍之间呈U形关联。报告睡眠时间≤5、6、8和≥9小时的个体发生认知障碍的比值比（95%置信区间）（以每日睡眠7小时为参照）分别为2.14（1.20 - 3.83）、1.13（0.67 - 1.89）、1.51（0.82 - 2.79）和5.37（1.62 - 17.80）（P≤0.01）。
夜间睡眠时间过短或过长是与认知障碍独立相关的重要睡眠相关因素，可能是认知障碍风险增加的一个有用标志物。
