Duan Lian, Zhang Li Xia, Zhang Shao Ping, Kong Jian, Zhi Hong, Zhang Ming, Lu Kai, Zhang Hong Wei
Department of Toxicology, Institute for Environmental Health and Related Product Safety, Chinese Center for Disease Control and Prevention, Beijing 100021, China.
Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Biomed Environ Sci. 2017 Oct;30(10):762-766. doi: 10.3967/bes2017.102.
To evaluate the potential risk of arteriosclerosis caused by desalinated seawater, Wistar rats were provided desalinated seawater over a 1-year period, and blood samples were collected at 0, 90, 180, and 360 days. Blood calcium, magnesium, and arteriosclerosis-related indicators were investigated. Female rats treated with desalinated seawater for 180 days showed lower magnesium levels than the control rats (P < 0.05). The calcium and magnesium levels in female rats and the magnesium level in male rats were lower than the levels in the controls, following treatment with desalinated seawater for 360 days (P < 0.05). Blood levels of arteriosclerosis-related lipid peroxidation indicators and C-reactive protein (CRP) in the treatment group did not differ from those in the controls. The levels of lipid peroxidation indicators and CRP in rats were not significantly affected by drinking desalinated seawater, and no increase in risk of arteriosclerosis was observed.
为评估淡化海水引起动脉硬化的潜在风险，在1年的时间里为Wistar大鼠提供淡化海水，并在第0、90、180和360天采集血样。对血钙、镁以及与动脉硬化相关的指标进行了研究。用淡化海水处理180天的雌性大鼠的镁水平低于对照大鼠（P<0.05）。用淡化海水处理360天后，雌性大鼠的钙和镁水平以及雄性大鼠的镁水平均低于对照组（P<0.05）。治疗组中与动脉硬化相关的脂质过氧化指标和C反应蛋白（CRP）的血液水平与对照组无差异。饮用淡化海水对大鼠脂质过氧化指标和CRP水平无显著影响，未观察到动脉硬化风险增加。
