α-乙烯基赖氨酸和α-乙烯基精氨酸是其同源脱羧酶的时间依赖性抑制剂。
α-VINYLLYSINE AND α-VINYLARGININE ARE TIME-DEPENDENT INHIBITORS OF THEIR COGNATE DECARBOXYLASES.
作者信息
Berkowitz David B, Jahng Wan-Jin, Pedersen Michelle L
机构信息
Department of Chemistry, University of Nebraska-Lincoln, Lincoln, NE 68588-0304.
出版信息
Bioorg Med Chem Lett. 1996 Sep 17;6(18):2151-2156. doi: 10.1016/0960-894X(96)00366-6.
Abstract
(±)-α-Vinyllysine and (±)-α-vinylarginine display time-dependent inhibition of L-lysine decarboxylase from , and L-arginine decarboxylase from , respectively. A complete Kitz-Wilson analysis has been performed using a modification of the Palcic continuous UV assay for decarboxylase activity.
摘要
（±）-α-乙烯基赖氨酸和（±）-α-乙烯基精氨酸分别对来自[具体来源1]的L-赖氨酸脱羧酶和来自[具体来源2]的L-精氨酸脱羧酶表现出时间依赖性抑制作用。已使用Palcic连续紫外法测定脱羧酶活性的改进方法进行了完整的Kitz-Wilson分析。
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