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使用汉方药物成功治疗了由草甘膦中毒引起的麻痹性肠梗阻。

Paralytic ileus induced by glyphosate intoxication successfully treated using Kampo medicine.

作者信息

Nakae Hajime, Kusanagi Misato, Okuyama Manabu, Igarashi Toshiko

机构信息

Department of Emergency and Critical Care Medicine Akita University Graduate School of Medicine Akita Japan.

出版信息

Acute Med Surg. 2014 Dec 11;2(3):214-218. doi: 10.1002/ams2.103. eCollection 2015 Jul.

DOI:10.1002/ams2.103
PMID:29123725
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5667246/
Abstract

CASE

A 65-year-old woman ingested glyphosate-surfactant herbicide in an attempt to commit suicide. She experienced glyphosate intoxication associated with multiple organ failure and developed a paralytic ileus. Daijokito, a traditional Japanese Kampo medicine was given to the patient to improve constipation and psychological symptoms. Next, rikkunshito was given to increase her gastric motility. Finally, daikenchuto was given to improve overall digestive peristalsis.

OUTCOME

All abdominal symptoms ultimately improved after treatment with daikenchuto.

CONCLUSION

Kampo medicines may help improve abdominal symptoms associated with glyphosate intoxication in cases where modern medical treatment alone proves inadequate.

摘要

病例

一名65岁女性为自杀而摄入了草甘膦-表面活性剂除草剂。她出现了与多器官功能衰竭相关的草甘膦中毒,并发展为麻痹性肠梗阻。给予患者日本传统汉方药大承气汤以改善便秘和心理症状。接下来,给予六君子汤以增强她的胃动力。最后,给予大建中汤以改善整体消化蠕动。

结果

使用大建中汤治疗后,所有腹部症状最终均得到改善。

结论

在仅靠现代医学治疗不足的情况下,汉方药可能有助于改善与草甘膦中毒相关的腹部症状。

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本文引用的文献

1
Heart rate-corrected QT interval predicts mortality in glyphosate-surfactant herbicide-poisoned patients.心率校正 QT 间期可预测草甘膦表面活性剂除草剂中毒患者的死亡率。
Am J Emerg Med. 2014 Mar;32(3):203-7. doi: 10.1016/j.ajem.2013.09.025. Epub 2013 Oct 1.
2
Herbicide roundup intoxication: successful treatment with continuous renal replacement therapy.
Am J Med. 2012 Aug;125(8):e1-2. doi: 10.1016/j.amjmed.2011.11.022. Epub 2012 Jun 7.
3
Influence of Dai-kenchu-to (DKT) on human portal blood flow.大建中汤对人体门静脉血流的影响。
Hepatogastroenterology. 2008 Mar-Apr;55(82-83):574-7.
4
Rikkunshito, an herbal medicine, suppresses cisplatin-induced anorexia in rats via 5-HT2 receptor antagonism.理气和中汤,一种草药制剂,通过拮抗5-HT2受体抑制顺铂诱导的大鼠厌食。
Gastroenterology. 2008 Jun;134(7):2004-13. doi: 10.1053/j.gastro.2008.02.078. Epub 2008 Feb 29.
5
Prokinetic effect of erythromycin after colorectal surgery: randomized, placebo-controlled, double-blind study.
Dis Colon Rectum. 2000 Mar;43(3):333-7. doi: 10.1007/BF02258298.