Kunitatsu Kosei, Ueda Kentaro, Iwasaki Yasuhiro, Yamazoe Shinji, Yonemitsu Takafumi, Kawazoe Yu, Kawashima Syuji, Shibata Naoaki, Kato Seiya
Department of Emergency and Critical Care Medicine Wakayama Medical University School of Medicine Wakayama Japan.
Acute Med Surg. 2016 May 10;3(4):345-350. doi: 10.1002/ams2.212. eCollection 2016 Oct.
The aims of this study were to investigate outcomes of abdominal trauma in patients with hemorrhagic shock requiring emergency laparotomy and clarify the beneficial effects of intra-aortic balloon occlusion (IABO) for intra-abdominal hemorrhage in patients with critically uncontrollable hemorrhagic shock (CUHS).
We reviewed 44 hemorrhagic shock patients who underwent emergency laparotomy for intra-abdominal hemorrhage over a 6-year period. Of these patients, we examined data for 19 subjects who underwent IABO during initial resuscitation to control massive intra-abdominal bleeding leading to CUHS.
The average Injury Severity Score and probability of survival (Ps) of the 44 patients were 27.6 ± 15.4 and 0.735 ± 0.304, respectively, and the overall survival rate was 77.3%. The differences in the Glasgow Coma Scale, lactate level, prothrombin time - international normalized ratio, and Ps between the two groups (21 responders and 23 non-responders) were statistically significant ( < 0.05). Intra-aortic balloon occlusion was attempted in 19 of 23 patients (82.6%) with CUHS, and there were no statistically significant differences in presenting Glasgow Coma Scale, body temperature, lactate, prothrombin time - international normalized ratio, or Revised Trauma Score between the survivors ( = 12) and non-survivors ( = 7). The only significant differences between these two groups were observed in Injury Severity Score ( = 0.047) and Ps ( = 0.007). In all patients, the balloons were successfully placed in 8.1 ± 3.3 min in the thoracic aorta, and a significant increase in systolic blood pressure was observed immediately after IABO.
The IABO procedure can be life-saving in the management of patients with CUHS arising from intra-abdominal hemorrhage, permitting transport to surgery.
本研究旨在调查需要紧急剖腹手术的失血性休克患者腹部创伤的结局,并阐明主动脉内球囊阻断术(IABO)对严重难以控制的失血性休克(CUHS)患者腹腔内出血的有益作用。
我们回顾了44例在6年期间因腹腔内出血接受紧急剖腹手术的失血性休克患者。在这些患者中,我们检查了19例在初始复苏期间接受IABO以控制导致CUHS的大量腹腔内出血的受试者的数据。
44例患者的平均损伤严重度评分和生存概率(Ps)分别为27.6±15.4和0.735±0.304,总生存率为77.3%。两组(21例反应者和23例无反应者)在格拉斯哥昏迷量表、乳酸水平、凝血酶原时间-国际标准化比值和Ps方面的差异具有统计学意义(<0.05)。23例CUHS患者中有19例(82.6%)尝试了主动脉内球囊阻断术,幸存者(n=12)和非幸存者(n=7)在出现时的格拉斯哥昏迷量表、体温、乳酸、凝血酶原时间-国际标准化比值或修订创伤评分方面无统计学显著差异。这两组之间唯一的显著差异在于损伤严重度评分(P=0.047)和Ps(P=0.007)。在所有患者中,球囊在胸主动脉成功放置的时间为8.1±3.3分钟,IABO后立即观察到收缩压显著升高。
IABO手术在处理由腹腔内出血引起的CUHS患者时可挽救生命,有助于转运至手术室进行手术。