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主动脉内球囊阻断复苏术治疗非创伤性腹腔内出血。

Resuscitative endovascular balloon occlusion of the aorta for non-traumatic intra-abdominal hemorrhage.

机构信息

University of Maryland Medical Center, 22 S Greene St., Baltimore, MD, 21201, USA.

出版信息

Eur J Trauma Emerg Surg. 2019 Aug;45(4):713-718. doi: 10.1007/s00068-018-0973-0. Epub 2018 Jun 19.

Abstract

BACKGROUND

Hemorrhagic shock is the second leading cause of death in blunt trauma and a significant cause of mortality in non-trauma patients. The increased use of resuscitative endovascular balloon occlusion of the aorta (REBOA) as a bridge to definitive control for massive hemorrhage has provided promising results in the trauma population. We describe an extension of this procedure to our hemodynamically unstable non-trauma patients.

METHODS

This is a retrospective review of patients requiring REBOA for end stage non-traumatic abdominal hemorrhage from our tertiary care facility. After excluding patients with trauma, supradiaphragmatic bleed and thoracic/abdominal aortic aneurysms, demographics, etiology of bleed, REBOA placement specifics, complications and outcomes were reviewed.

RESULTS

From August 2013 to August 2016, 11 patients were identified requiring REBOA placement for hemodynamic instability from non-traumatic abdominal hemorrhage. Average patient age was 54.9 (SD 15.2). Sixty-four percent suffered cardiac arrest prior to REBOA, with mean shock index of 1.29. Average time from diagnosis of shock (MAP ≤ 65) or signs of bleeding to placement of REBOA was 177 min. The leading etiologies of hemorrhage were ruptured visceral aneurysm and massive upper gastrointestinal bleed. REBOA was placed by both acute care and vascular surgeons. The procedure was mainly completed in the operating room in 82% of the patients and at the bedside in 18%. One patient expired before operative repair. Definitive surgical control of the source of bleeding was obtained by open surgical approach (n = 6) and combined surgical and endovascular approach (n = 4). In-hospital survival was 64%. There were no local complications related to REBOA placement.

CONCLUSION

Similar to the trauma population, REBOA is an adjunctive technique for proximal control of bleeding as well as resuscitation in end stage non-traumatic intra-abdominal hemorrhage. We propose an algorithmic approach to REBOA use in this population and a larger prospective review is necessary to determine both the timing of REBOA placement and which non-traumatic patients may benefit from this technique.

LEVEL OF EVIDENCE

V.

STUDY TYPE

Brief report.

摘要

背景

失血性休克是钝性创伤导致死亡的第二大原因,也是非创伤患者死亡的重要原因。在创伤人群中,使用复苏性血管内球囊阻断主动脉(REBOA)作为控制大出血的桥梁,已经取得了有希望的结果。我们将这一方法扩展到血流动力学不稳定的非创伤患者。

方法

这是对我们的三级保健机构中因终末期非创伤性腹部出血而需要 REBOA 的患者进行的回顾性研究。排除创伤、膈上出血和胸/腹主动脉瘤患者后,我们回顾了患者的人口统计学特征、出血原因、REBOA 放置的具体情况、并发症和结局。

结果

2013 年 8 月至 2016 年 8 月,我们共确定了 11 例因非创伤性腹部出血导致血流动力学不稳定而需要进行 REBOA 放置的患者。患者平均年龄为 54.9(标准差 15.2)岁。64%的患者在放置 REBOA 前发生心脏骤停,休克指数平均为 1.29。从休克(MAP≤65)或出血迹象诊断到放置 REBOA 的平均时间为 177 分钟。出血的主要病因是内脏动脉瘤破裂和上消化道大出血。REBOA 由急性护理和血管外科医生放置。该手术主要在 82%的患者中在手术室完成,在 18%的患者中在床边完成。有 1 例患者在手术修复前死亡。通过开放性手术(n=6)和联合手术和血管内治疗(n=4)获得了出血源的确定性手术控制。院内生存率为 64%。没有与 REBOA 放置相关的局部并发症。

结论

与创伤人群一样,REBOA 是控制终末期非创伤性腹腔内出血近端出血和复苏的辅助技术。我们提出了一种在该人群中使用 REBOA 的算法方法,需要更大的前瞻性研究来确定 REBOA 放置的时机以及哪些非创伤性患者可能受益于该技术。

证据水平

V

研究类型

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