Pennington D G, McBride L R, Swartz M T, Kanter K R, Kaiser G C, Barner H B, Miller L W, Naunheim K S, Fiore A C, Willman V L
Department of Surgery, St. Louis University Hospital, Missouri 63104.
Ann Thorac Surg. 1989 Jan;47(1):130-5. doi: 10.1016/0003-4975(89)90254-3.
In spite of recent improvements in cardiac surgery, a small percentage of patients have severe postcardiotomy ventricular failure refractory to drugs and the intraaortic balloon. In our experience, the Pierce-Donachy external pneumatic ventricular assist device has proved to be one of the most effective devices for these patients. Since 1981, 30 patients aged 15 to 71 years (mean age, 52 years) with profound cardiogenic shock refractory to conventional therapy after cardiotomy were supported with the Pierce-Donachy ventricular assist device. Fourteen required left ventricular support, 7 needed right ventricular support with an intraaortic balloon, and 9 had biventricular assistance. Duration of support ranged from three hours to 22 days (mean length, 3.6 days). Seven of the first 11 patients seen died in the operating room of bleeding, biventricular failure, or both. However, 16 patients (53%) had improved cardiac function, 15 (50%) were weaned, and 11 (37%) were discharged. Of the last 19 patients in the series, 47% survived. Factors affecting survival were myocardial infarction (75%) and renal failure (90%). Common complications were bleeding (73%) and biventricular failure (83%).
尽管心脏外科手术近来有所改进,但仍有一小部分患者在心脏切开术后出现严重的心室衰竭,对药物和主动脉内球囊治疗无效。根据我们的经验,皮尔斯 - 多纳希体外气动心室辅助装置已被证明是治疗这些患者最有效的装置之一。自1981年以来,30例年龄在15至71岁(平均年龄52岁)的患者,在心脏切开术后因传统治疗无效而出现严重的心源性休克,接受了皮尔斯 - 多纳希心室辅助装置的支持治疗。其中14例需要左心室支持,7例需要右心室支持并使用主动脉内球囊,9例接受双心室辅助。支持时间从3小时到22天不等(平均时长为3.6天)。最初诊治的11例患者中有7例在手术室死于出血、双心室衰竭或两者皆有。然而,16例患者(53%)的心功能有所改善,15例(50%)成功撤机,11例(37%)出院。在该系列的最后19例患者中,47%存活。影响生存的因素是心肌梗死(75%)和肾衰竭(90%)。常见并发症是出血(73%)和双心室衰竭(83%)。