胰腺癌肺转移灶切除术
Resection for Pancreatic Cancer Lung Metastases.
作者信息
Okui Masayuki, Yamamichi Takashi, Asakawa Ayaka, Harada Masahiko, Horio Hirotoshi
机构信息
Department of Thoracic Surgery, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital.
出版信息
Korean J Thorac Cardiovasc Surg. 2017 Oct;50(5):326-328. doi: 10.5090/kjtcs.2017.50.5.326. Epub 2017 Oct 5.
BACKGROUND
Pancreatic cancer is a highly aggressive solid tumor. Patients with metastases from pancreatic cancer have poor survival rates. Here, we report the outcomes of 6 patients for whom resection of lung metastases was performed after a pancreatectomy to treat pancreatic cancer.
METHODS
We retrospectively reviewed the perioperative clinical data of patients with lung metastases resulting from primary pancreatic cancer who were treated with lung resection between 2008 and 2015. We report 6 cases where lung resection was performed to treat lung metastases after a pancreatectomy.
RESULTS
The number of lung metastases was 1 in 5 cases and 2 in 1 case. The surgical procedures performed to treat the lung metastases included 4 wedge resections and 2 lobectomies. The cell type of the primary tumor and metastases was tubular adenocarcinoma in 5 cases and intraductal papillary-mucinous carcinoma in 1 case. All 6 patients survived with a mean follow-up period of 65.6 months, although the disease recurred in 2 patients.
CONCLUSION
Resection of lung metastases resulting from primary pancreatic cancer may lengthen survival, provided the patient can tolerate surgery.
背景
胰腺癌是一种侵袭性很强的实体瘤。胰腺癌转移患者的生存率很低。在此，我们报告6例胰腺癌患者在接受胰腺切除术后又进行了肺转移灶切除的治疗结果。
方法
我们回顾性分析了2008年至2015年间因原发性胰腺癌导致肺转移并接受肺切除术治疗的患者的围手术期临床资料。我们报告了6例在胰腺切除术后进行肺转移灶切除的病例。
结果
5例患者有1个肺转移灶，1例患者有2个肺转移灶。治疗肺转移灶所采用的手术方式包括4例楔形切除术和2例肺叶切除术。5例患者的原发肿瘤和转移灶的细胞类型为管状腺癌，1例为导管内乳头状黏液癌。所有6例患者均存活，平均随访期为65.6个月，不过有2例患者疾病复发。
结论
如果患者能够耐受手术，切除原发性胰腺癌导致的肺转移灶可能会延长生存期。
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